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Fgfbp3 fibroblast growth factor binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 72514, updated on 9-Dec-2024

Summary

Official Symbol
Fgfbp3provided by MGI
Official Full Name
fibroblast growth factor binding protein 3provided by MGI
Primary source
MGI:MGI:1919764
See related
Ensembl:ENSMUSG00000047632 AllianceGenome:MGI:1919764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fgf-bp3; 2610306H15Rik
Summary
Enables fibroblast growth factor binding activity. Involved in adult behavior; positive regulation of ERK1 and ERK2 cascade; and positive regulation of nervous system process. Predicted to be located in extracellular region. Is expressed in several structures, including central nervous system; future prosencephalon; male reproductive gland or organ; notochord; and primitive endoderm. Orthologous to human FGFBP3 (fibroblast growth factor binding protein 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in whole brain E14.5 (RPKM 18.3), CNS E14 (RPKM 17.0) and 20 other tissues See more
Orthologs
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Genomic context

See Fgfbp3 in Genome Data Viewer
Location:
19 C2; 19 32.01 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (36894950..36896999, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (36917550..36919599, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46030 Neighboring gene predicted gene, 57662 Neighboring gene tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 Neighboring gene STARR-seq mESC enhancer starr_46034 Neighboring gene VISTA enhancer mm1641 Neighboring gene STARR-seq mESC enhancer starr_46037 Neighboring gene STARR-positive B cell enhancer ABC_E11029 Neighboring gene STARR-seq mESC enhancer starr_46040 Neighboring gene STARR-positive B cell enhancer ABC_E4277 Neighboring gene STARR-seq mESC enhancer starr_46041 Neighboring gene B-TFIID TATA-box binding protein associated factor 1 Neighboring gene cytoplasmic polyadenylation element binding protein 3 Neighboring gene RIKEN cDNA A330032B11 gene

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fibroblast growth factor binding PubMed 
enables fibroblast growth factor binding  
enables growth factor binding  
enables heparin binding  
Component Evidence Code Pubs
located_in extracellular region  

General protein information

Preferred Names
fibroblast growth factor-binding protein 3
Names
FGF-binding protein 3
FGFBP-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028263.1NP_082539.2  fibroblast growth factor-binding protein 3 precursor

    See identical proteins and their annotated locations for NP_082539.2

    Status: VALIDATED

    Source sequence(s)
    BC055778
    Consensus CDS
    CCDS29774.2
    UniProtKB/Swiss-Prot
    Q1HCM0, Q7TNS6, Q8CDW7
    UniProtKB/TrEMBL
    A0A0R4J0R6
    Related
    ENSMUSP00000159137.2, ENSMUST00000238948.2
    Conserved Domains (1) summary
    pfam06473
    Location:31250
    FGF-BP1; FGF binding protein 1 (FGF-BP1)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    36894950..36896999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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