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Acbd6 acyl-Coenzyme A binding domain containing 6 [ Mus musculus (house mouse) ]

Gene ID: 72482, updated on 11-Apr-2024

Summary

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Official Symbol
Acbd6provided by MGI
Official Full Name
acyl-Coenzyme A binding domain containing 6provided by MGI
Primary source
MGI:MGI:1919732
See related
Ensembl:ENSMUSG00000033701 AllianceGenome:MGI:1919732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610010G04Rik; 2610100E10Rik
Summary
Predicted to enable fatty-acyl-CoA binding activity and lipid binding activity. Predicted to be located in cytoplasm. Orthologous to human ACBD6 (acyl-CoA binding domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 57.6), ovary adult (RPKM 37.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Acbd6 in Genome Data Viewer
Location:
1 G3; 1 66.92 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155433845..155564120)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155558099..155687474)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02725 Neighboring gene predicted gene, 31772 Neighboring gene predicted gene 5532 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157405138-157405321 Neighboring gene STARR-positive B cell enhancer ABC_E9484 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157423836-157424136 Neighboring gene STARR-seq mESC enhancer starr_02727 Neighboring gene LIM homeobox protein 4 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157659814-157660115 Neighboring gene quiescin Q6 sulfhydryl oxidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC106946, MGC144461, MGC144462

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fatty-acyl-CoA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acyl-CoA-binding domain-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145781.1 → NP_001139253.1  acyl-CoA-binding domain-containing protein 6 isoform 2

    See identical proteins and their annotated locations for NP_001139253.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK082937, AK165836
    Consensus CDS
    CCDS48398.1
    UniProtKB/Swiss-Prot
    Q9D061
    Related
    ENSMUSP00000095136.4, ENSMUST00000097529.5
    Conserved Domains (1) summary
    pfam00887
    Location:44 → 123
    ACBP; Acyl CoA binding protein

  2. NM_026683.1 → NP_080959.1  acyl-CoA-binding domain-containing protein 6 isoform 3

    See identical proteins and their annotated locations for NP_080959.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK002470, AK082937
    Consensus CDS
    CCDS48397.1
    UniProtKB/Swiss-Prot
    Q9D061
    Related
    ENSMUSP00000079035.7, ENSMUST00000080138.13
    Conserved Domains (1) summary
    pfam00887
    Location:44 → 123
    ACBP; Acyl CoA binding protein

  3. NM_028250.3 → NP_082526.2  acyl-CoA-binding domain-containing protein 6 isoform 1

    See identical proteins and their annotated locations for NP_082526.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AA260937, AK082937, BC115580
    Consensus CDS
    CCDS15385.1
    UniProtKB/Swiss-Prot
    Q3TMN7, Q9D061, Q9DCU4
    UniProtKB/TrEMBL
    Q14BV7
    Related
    ENSMUSP00000049124.4, ENSMUST00000035560.9
    Conserved Domains (4) summary
    cd00204
    Location:165 → 261
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00887
    Location:44 → 123
    ACBP; Acyl CoA binding protein
    pfam12796
    Location:166 → 255
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:191 → 222
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    155433845..155564120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529883.5 → XP_006529946.1  acyl-CoA-binding domain-containing protein 6 isoform X1

    Conserved Domains (2) summary
    sd00045
    Location:98 → 129
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:73 → 162
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. XR_387197.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D061.2 GenPept UniProtKB/Swiss-Prot:Q9D061

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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