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Ceacam18 CEA cell adhesion molecule 18 [ Mus musculus (house mouse) ]

Gene ID: 72431, updated on 21-Apr-2024

Summary

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Official Symbol
Ceacam18provided by MGI
Official Full Name
CEA cell adhesion molecule 18provided by MGI
Primary source
MGI:MGI:1919681
See related
Ensembl:ENSMUSG00000030472 AllianceGenome:MGI:1919681
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010110O04Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human CEACAM18 (CEA cell adhesion molecule 18). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum adult (RPKM 20.6), small intestine adult (RPKM 20.3) and 2 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 B3; 7 28.25 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43284094..43298719)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43634617..43649295)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9290 Neighboring gene zinc finger protein 719 Neighboring gene STARR-seq mESC enhancer starr_18778 Neighboring gene STARR-seq mESC enhancer starr_18779 Neighboring gene zinc finger protein 819 Neighboring gene sialic acid binding Ig-like lectin E Neighboring gene uncharacterized LOC118567526 Neighboring gene STARR-positive B cell enhancer ABC_E11351

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 18
Names
CEA-related cell adhesion molecule 1
carcinoembryonic antigen-related cell adhesion molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419040.1 → NP_001405969.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC151989, AC154108

  2. NM_028236.2 → NP_082512.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform 1 precursor

    See identical proteins and their annotated locations for NP_082512.1

    Status: VALIDATED

    Source sequence(s)
    AC151989, AC154108
    Consensus CDS
    CCDS21177.1
    UniProtKB/Swiss-Prot
    Q9D871
    Related
    ENSMUSP00000032663.9, ENSMUST00000032663.10
    Conserved Domains (2) summary
    smart00410
    Location:243 → 315
    IG_like; Immunoglobulin like
    cl11960
    Location:42 → 134
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    43284094..43298719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312326.1 → XP_017167815.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X1

    Conserved Domains (2) summary
    cd05774
    Location:68 → 170
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    cl11960
    Location:283 → 338
    Ig; Immunoglobulin domain

  2. XM_017312327.1 → XP_017167816.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X2

    Conserved Domains (2) summary
    cd05774
    Location:68 → 170
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    cl11960
    Location:192 → 247
    Ig; Immunoglobulin domain

  3. XM_017312328.1 → XP_017167817.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X4

    Conserved Domains (1) summary
    cl11960
    Location:94 → 149
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D871.1 GenPept UniProtKB/Swiss-Prot:Q9D871

Gene LinkOut

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