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B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [ Mus musculus (house mouse) ]

Gene ID: 72297, updated on 5-Mar-2024

Summary

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Official Symbol
B3gnt3provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3provided by MGI
Primary source
MGI:MGI:2152535
See related
Ensembl:ENSMUSG00000031803 AllianceGenome:MGI:2152535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210008L19Rik
Summary
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 175.6), duodenum adult (RPKM 146.7) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 B3.3; 8 34.43 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (72144017..72155270, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71691373..71702626, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:74157112-74157221 Neighboring gene unc-13 homolog A Neighboring gene microRNA 6769b Neighboring gene STARR-positive B cell enhancer ABC_E5015 Neighboring gene STARR-positive B cell enhancer ABC_E10509 Neighboring gene STARR-seq mESC enhancer starr_21826 Neighboring gene Janus kinase 3 Neighboring gene insulin-like 3 Neighboring gene STARR-seq mESC enhancer starr_21829 Neighboring gene predicted gene 45756 Neighboring gene CCR4-NOT transcription complex, subunit 8 pseudogene Neighboring gene FCH domain only 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in poly-N-acetyllactosamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
Names
BGnT-3
beta-1,3-Gn-T3
beta-1,3-N-acetylglucosaminyltransferase 3
beta3Gn-T3
core 1 beta-1,3-N-acetylglucosaminyltransferase
core 1 extending beta-1,3-N-acetylglucosaminyltransferase
core1-beta3GlcNAcT
NP_082465.3
XP_006509815.1
XP_006509816.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028189.3 → NP_082465.3  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

    See identical proteins and their annotated locations for NP_082465.3

    Status: VALIDATED

    Source sequence(s)
    AC162033, AY039028, BY753510
    Consensus CDS
    CCDS22405.1
    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Related
    ENSMUSP00000034260.8, ENSMUST00000034260.9
    Conserved Domains (1) summary
    cl21608
    Location:122 → 311
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    72144017..72155270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509753.4 → XP_006509816.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1

    See identical proteins and their annotated locations for XP_006509816.1

    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Conserved Domains (1) summary
    cl21608
    Location:122 → 311
    Galactosyl_T; Galactosyltransferase

  2. XM_006509752.4 → XP_006509815.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1

    See identical proteins and their annotated locations for XP_006509815.1

    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Conserved Domains (1) summary
    cl21608
    Location:122 → 311
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5JCS9.1 GenPept UniProtKB/Swiss-Prot:Q5JCS9

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