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Fam186a family with sequence similarity 186, member A [ Mus musculus (house mouse) ]

Gene ID: 72277, updated on 5-Mar-2024

Summary

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Official Symbol
Fam186aprovided by MGI
Official Full Name
family with sequence similarity 186, member Aprovided by MGI
Primary source
MGI:MGI:2685766
See related
Ensembl:ENSMUSG00000045350 AllianceGenome:MGI:2685766
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm920; 1700030F18Rik
Summary
Orthologous to human FAM186A (family with sequence similarity 186 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 20.8) See more
Orthologs
human all
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Genomic context

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Location:
15 F1; 15 56.13 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (99816226..99864974, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99918345..99967093, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700121M21 gene Neighboring gene ubiquinol-cytochrome c reductase hinge protein, pseudogene 1 Neighboring gene ribosomal protein S10 pseudogene Neighboring gene predicted gene, 21917 Neighboring gene RIKEN cDNA 2310068J16 gene Neighboring gene STARR-positive B cell enhancer ABC_E3157 Neighboring gene La ribonucleoprotein 4 Neighboring gene STARR-seq mESC enhancer starr_39735 Neighboring gene STARR-positive B cell enhancer mm9_chr15:99890852-99891153 Neighboring gene disco interacting protein 2 homolog B Neighboring gene STARR-seq mESC enhancer starr_39737

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM186A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028180.3 → NP_082456.1  protein FAM186A

    See identical proteins and their annotated locations for NP_082456.1

    Status: VALIDATED

    Source sequence(s)
    AC138177, AK006542
    Consensus CDS
    CCDS37207.1
    UniProtKB/Swiss-Prot
    Q9D9R9
    Related
    ENSMUSP00000053434.9, ENSMUST00000062631.15

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    99816226..99864974 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248785.1 → XP_030104645.1  protein FAM186A isoform X2

    UniProtKB/TrEMBL
    K3W4Q5
    Related
    ENSMUSP00000097783.5, ENSMUST00000100209.6
    Conserved Domains (2) summary
    PHA03247
    Location:1228 → 1632
    PHA03247; large tegument protein UL36; Provisional
    COG5043
    Location:25 → 255
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

  2. XM_036159601.1 → XP_036015494.1  protein FAM186A isoform X3

    UniProtKB/TrEMBL
    K3W4Q5
    Conserved Domains (2) summary
    PHA03247
    Location:1155 → 1594
    PHA03247; large tegument protein UL36; Provisional
    COG5043
    Location:25 → 255
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

  3. XM_036159600.1 → XP_036015493.1  protein FAM186A isoform X1

    UniProtKB/TrEMBL
    K3W4Q5
    Conserved Domains (2) summary
    PHA03247
    Location:1228 → 1632
    PHA03247; large tegument protein UL36; Provisional
    COG5043
    Location:25 → 255
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

  4. XM_036159602.1 → XP_036015495.1  protein FAM186A isoform X4

    UniProtKB/TrEMBL
    K3W4Q5
    Conserved Domains (1) summary
    PHA03247
    Location:1079 → 1483
    PHA03247; large tegument protein UL36; Provisional

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001162867.1: Suppressed sequence

    Description
    NM_001162867.1: This RefSeq was temporarily suppressed because the CDS was partial.

  2. NM_001195694.1: Suppressed sequence

    Description
    NM_001195694.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D9R9.2 GenPept UniProtKB/Swiss-Prot:Q9D9R9

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