U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc37a3 solute carrier family 37 (glycerol-3-phosphate transporter), member 3 [ Mus musculus (house mouse) ]

Gene ID: 72144, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Slc37a3provided by MGI
Official Full Name
solute carrier family 37 (glycerol-3-phosphate transporter), member 3provided by MGI
Primary source
MGI:MGI:1919394
See related
Ensembl:ENSMUSG00000029924 AllianceGenome:MGI:1919394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610507O21Rik
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within carbohydrate transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human SLC37A3 (solute carrier family 37 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 8.6), CNS E18 (RPKM 8.4) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Slc37a3 in Genome Data Viewer
Location:
6 B1; 6 18.11 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (39311704..39354659, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (39334770..39377725, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34147 Neighboring gene predicted gene, 53067 Neighboring gene predicted gene, 26008 Neighboring gene STARR-seq mESC enhancer starr_15634 Neighboring gene STARR-seq mESC enhancer starr_15635 Neighboring gene STARR-seq mESC enhancer starr_15639 Neighboring gene STARR-positive B cell enhancer ABC_E4822 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:39329756-39330023 Neighboring gene RAB19, member RAS oncogene family Neighboring gene makorin, ring finger protein, 1 Neighboring gene STARR-seq mESC enhancer starr_15648 Neighboring gene predicted gene 10244

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Yu Z, et al. Elife, 2018 May 10. PMID 29745899, Free PMC Article
  2. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene. Amson RB, et al. Proc Natl Acad Sci U S A, 1996 Apr 30. PMID 8632996, Free PMC Article
  3. Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation. Kuninger D, et al. Genomics, 2004 Nov. PMID 15475267
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC106297

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables xenobiotic transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables xenobiotic transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in xenobiotic transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in xenobiotic transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in lysosomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
sugar phosphate exchanger 3
Names
solute carrier family 37 member 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361617.1 → NP_001348546.1  sugar phosphate exchanger 3 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC153624
    Consensus CDS
    CCDS20020.1
    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  2. NM_001361618.1 → NP_001348547.1  sugar phosphate exchanger 3 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC153624
    Consensus CDS
    CCDS20020.1
    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  3. NM_001361619.1 → NP_001348548.1  sugar phosphate exchanger 3 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC153624
    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cl27298
    Location:114 → 462
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]

  4. NM_028123.3 → NP_082399.3  sugar phosphate exchanger 3 isoform a

    See identical proteins and their annotated locations for NP_082399.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
    Source sequence(s)
    AC153624, AK076213, CJ161523
    Consensus CDS
    CCDS20020.1
    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Related
    ENSMUSP00000087709.5, ENSMUST00000090243.8
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

RNA

  1. NR_155076.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' end and lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC153624

  2. NR_155077.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' end and lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC153624

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    39311704..39354659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506658.3 → XP_006506721.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506721.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  2. XM_006506665.3 → XP_006506728.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506728.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  3. XM_006506661.4 → XP_006506724.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506724.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  4. XM_006506659.4 → XP_006506722.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506722.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  5. XM_036152320.1 → XP_036008213.1  sugar phosphate exchanger 3 isoform X2

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  6. XM_017321757.1 → XP_017177246.1  sugar phosphate exchanger 3 isoform X2

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  7. XM_006506663.5 → XP_006506726.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506726.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  8. XM_030255602.1 → XP_030111462.1  sugar phosphate exchanger 3 isoform X2

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  9. XM_006506666.4 → XP_006506729.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506729.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  10. XM_036152319.1 → XP_036008212.1  sugar phosphate exchanger 3 isoform X1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  11. XM_006506667.4 → XP_006506730.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506730.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  12. XM_006506664.4 → XP_006506727.1  sugar phosphate exchanger 3 isoform X1

    See identical proteins and their annotated locations for XP_006506727.1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  13. XM_030255601.1 → XP_030111461.1  sugar phosphate exchanger 3 isoform X1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  14. XM_036152318.1 → XP_036008211.1  sugar phosphate exchanger 3 isoform X1

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    Conserved Domains (1) summary
    cd17342
    Location:20 → 468
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

  15. XM_017321758.2 → XP_017177247.1  sugar phosphate exchanger 3 isoform X2

    UniProtKB/Swiss-Prot
    Q3TIT8, Q4FZD9, Q8BVX2
    UniProtKB/TrEMBL
    A0A0R4J133
    Conserved Domains (1) summary
    cd17342
    Location:20 → 476
    MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TIT8.1 GenPept UniProtKB/Swiss-Prot:Q3TIT8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous