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Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 [ Mus musculus (house mouse) ]

Gene ID: 72094, updated on 8-Feb-2024

Summary

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Official Symbol
Ugt2a3provided by MGI
Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide A3provided by MGI
Primary source
MGI:MGI:1919344
See related
Ensembl:ENSMUSG00000035780 AllianceGenome:MGI:1919344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2010321J07Rik
Summary
Predicted to enable glucuronosyltransferase activity. Predicted to be involved in cellular glucuronidation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in nervous system; nose; and olfactory epithelium. Orthologous to human UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 48.1), duodenum adult (RPKM 5.4) and 2 other tissues See more
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Genomic context

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See Ugt2a3 in Genome Data Viewer
Location:
5 E1; 5 43.56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (87472694..87485054, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (87324972..87337195, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B37 Neighboring gene STARR-seq mESC enhancer starr_13557 Neighboring gene predicted gene 7646 Neighboring gene UDP-glucuronosyltransferase 2A1-like Neighboring gene isopentenyl-diphosphate delta isomerase, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Chen S, et al. Proc Natl Acad Sci U S A, 2017 Feb 21. PMID 28167773, Free PMC Article
  2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular glucuronidation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-glucuronosyltransferase 2A3
Names
UDPGT 2A3
NP_082370.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028094.4 → NP_082370.2  UDP-glucuronosyltransferase 2A3 precursor

    See identical proteins and their annotated locations for NP_082370.2

    Status: VALIDATED

    Source sequence(s)
    AC101835
    Consensus CDS
    CCDS19387.1
    UniProtKB/Swiss-Prot
    Q8BWQ1, Q8R129, Q9D811
    Related
    ENSMUSP00000031195.3, ENSMUST00000031195.3
    Conserved Domains (2) summary
    PHA03392
    Location:268 → 507
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:25 → 526
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    87472694..87485054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BWQ1.1 GenPept UniProtKB/Swiss-Prot:Q8BWQ1

Gene LinkOut

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