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Haus5 HAUS augmin-like complex, subunit 5 [ Mus musculus (house mouse) ]

Gene ID: 71909, updated on 21-Apr-2024

Summary

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Official Symbol
Haus5provided by MGI
Official Full Name
HAUS augmin-like complex, subunit 5provided by MGI
Primary source
MGI:MGI:1919159
See related
Ensembl:ENSMUSG00000078762 AllianceGenome:MGI:1919159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310022K01Rik
Summary
Predicted to be involved in centrosome cycle and spindle assembly. Predicted to act upstream of or within cell division. Predicted to be located in mitotic spindle microtubule. Predicted to be part of HAUS complex. Predicted to be active in centrosome. Orthologous to human HAUS5 (HAUS augmin like complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 14.0), liver E14.5 (RPKM 13.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 B1; 7 18.95 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30353133..30364419, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30653708..30664994, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18529 Neighboring gene ets variant 2 Neighboring gene RNA binding motif protein 42 Neighboring gene STARR-positive B cell enhancer ABC_E545 Neighboring gene STARR-seq mESC enhancer starr_18530 Neighboring gene STARR-positive B cell enhancer ABC_E6533 Neighboring gene PMIS2 transmembrane protein Neighboring gene predicted gene, 53357

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery. Baines K, et al. Autophagy Rep, 2022. PMID 35449600, Free PMC Article
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spindle assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of HAUS complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of HAUS complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in mitotic spindle microtubule ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
HAUS augmin-like complex subunit 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027999.1 → NP_082275.1  HAUS augmin-like complex subunit 5

    See identical proteins and their annotated locations for NP_082275.1

    Status: VALIDATED

    Source sequence(s)
    AI448816, BC089002, BY151175
    Consensus CDS
    CCDS52180.1
    UniProtKB/Swiss-Prot
    Q08EB3, Q0VF86, Q5HZI7, Q6ZQ35, Q8CIK2, Q9D786
    Related
    ENSMUSP00000019697.9, ENSMUST00000019697.9
    Conserved Domains (1) summary
    pfam14817
    Location:8 → 615
    HAUS5; HAUS augmin-like complex subunit 5

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    30353133..30364419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D786.1 GenPept UniProtKB/Swiss-Prot:Q9D786

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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