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Chst13 carbohydrate sulfotransferase 13 [ Mus musculus (house mouse) ]

Gene ID: 71797, updated on 5-Mar-2024

Summary

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Official Symbol
Chst13provided by MGI
Official Full Name
carbohydrate sulfotransferase 13provided by MGI
Primary source
MGI:MGI:1919047
See related
Ensembl:ENSMUSG00000056643 AllianceGenome:MGI:1919047
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C4ST-3; 1110067M19Rik
Summary
Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity and chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and skeleton. Orthologous to human CHST13 (carbohydrate sulfotransferase 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 13.9), placenta adult (RPKM 12.7) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Chst13 in Genome Data Viewer
Location:
6 D1; 6 40.13 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (90285333..90302167, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (90308351..90325185, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 54 Neighboring gene cDNA sequence BC048671 Neighboring gene urocanase domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E10392 Neighboring gene STARR-seq mESC enhancer starr_16614 Neighboring gene ZXD family zinc finger C Neighboring gene STARR-seq mESC enhancer starr_16615

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance. Akita K, et al. Stem Cells, 2008 Mar. PMID 18079434
  2. Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells. Schaberg E, et al. Front Cell Dev Biol, 2021. PMID 34169071, Free PMC Article
  3. Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. van der Zwaag B, et al. Genomics, 2005 Jul. PMID 15953540
  4. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetylgalactosamine 4-O-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables chondroitin 4-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
carbohydrate sulfotransferase 13
Names
carbohydrate (chondroitin 4) sulfotransferase 13
NP_082204.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027928.1 → NP_082204.1  carbohydrate sulfotransferase 13 precursor

    Status: VALIDATED

    Source sequence(s)
    AC122521
    Consensus CDS
    CCDS51847.1
    UniProtKB/TrEMBL
    D3Z6E3
    Related
    ENSMUSP00000064897.5, ENSMUST00000070890.6
    Conserved Domains (1) summary
    pfam03567
    Location:99 → 327
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    90285333..90302167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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