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Rbm43 RNA binding motif protein 43 [ Mus musculus (house mouse) ]

Gene ID: 71684, updated on 5-Mar-2024

Summary

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Official Symbol
Rbm43provided by MGI
Official Full Name
RNA binding motif protein 43provided by MGI
Primary source
MGI:MGI:1918934
See related
Ensembl:ENSMUSG00000036249 AllianceGenome:MGI:1918934
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610033I05Rik
Summary
Predicted to enable RNA binding activity. Is expressed in central nervous system and sensory organ. Orthologous to human RBM43 (RNA binding motif protein 43). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 5.7), liver E14.5 (RPKM 5.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rbm43 in Genome Data Viewer
Location:
2 C1.1; 2 29.98 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (51814460..51825175, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (51924448..51935163, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13490 Neighboring gene STARR-seq mESC enhancer starr_04472 Neighboring gene STARR-seq mESC enhancer starr_04473 Neighboring gene peptidylprolyl isomerase A (Ppia) pseudogene 2_635.1 Neighboring gene predicted gene 13495 Neighboring gene chaperonin containing Tcp1, subunit 8 (theta) pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The genetic program of hematopoietic stem cells. Phillips RL, et al. Science, 2000 Jun 2. PMID 10834841
  2. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
RNA-binding protein 43

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001141981.2 → NP_001135453.1  RNA-binding protein 43 isoform b

    See identical proteins and their annotated locations for NP_001135453.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Related
    ENSMUSP00000099828.2, ENSMUST00000102767.8
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. NM_001141982.2 → NP_001135454.1  RNA-binding protein 43 isoform b

    See identical proteins and their annotated locations for NP_001135454.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Related
    ENSMUSP00000126129.2, ENSMUST00000165313.2
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. NM_001355604.1 → NP_001342533.1  RNA-binding protein 43 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Related
    ENSMUSP00000099829.2, ENSMUST00000102768.8
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. NM_001355606.1 → NP_001342535.1  RNA-binding protein 43 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. NM_001355607.1 → NP_001342536.1  RNA-binding protein 43 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  6. NM_001355608.1 → NP_001342537.1  RNA-binding protein 43 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks an alternate exon compared to variant 1. The resulting isoform (a) has a longer and distinct N-terminus compared to isoform b.
    Source sequence(s)
    AL929026
    Conserved Domains (1) summary
    cl17169
    Location:113 → 173
    RRM_SF; RNA recognition motif (RRM) superfamily

  7. NM_030243.5 → NP_084519.1  RNA-binding protein 43 isoform b

    See identical proteins and their annotated locations for NP_084519.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shorter isoform (b). Variants 1-6 all encode the same isoform (b).
    Source sequence(s)
    AL929026
    Consensus CDS
    CCDS16030.1
    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    51814460..51825175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498340.3 → XP_006498403.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006498403.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. XM_011239185.2 → XP_011237487.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_011237487.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_030252091.1 → XP_030107951.1  RNA-binding protein 43 isoform X1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. XM_011239187.1 → XP_011237489.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_011237489.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. XM_006498343.5 → XP_006498406.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006498406.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  6. XM_006498345.3 → XP_006498408.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006498408.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily

  7. XM_006498341.3 → XP_006498404.1  RNA-binding protein 43 isoform X1

    See identical proteins and their annotated locations for XP_006498404.1

    UniProtKB/Swiss-Prot
    Q99J64
    Conserved Domains (1) summary
    cl17169
    Location:15 → 75
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99J64.1 GenPept UniProtKB/Swiss-Prot:Q99J64

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