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Wdr27 WD repeat domain 27 [ Mus musculus (house mouse) ]

Gene ID: 71682, updated on 5-Mar-2024

Summary

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Official Symbol
Wdr27provided by MGI
Official Full Name
WD repeat domain 27provided by MGI
Primary source
MGI:MGI:1918932
See related
Ensembl:ENSMUSG00000046991 AllianceGenome:MGI:1918932
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610012K18Rik
Summary
Predicted to be located in nucleoplasm. Orthologous to human WDR27 (WD repeat domain 27). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 4.5), ovary adult (RPKM 0.4) and 4 other tissues See more
Orthologs
human all
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Genomic context

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See Wdr27 in Genome Data Viewer
Location:
17 A2; 17 8.95 cM
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15005092..15163540, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (14784829..14943259, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene thrombospondin 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_41895 Neighboring gene predicted gene, 23352 Neighboring gene STARR-seq mESC enhancer starr_41897 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:15046536-15046719 Neighboring gene RIKEN cDNA 1600012H06 gene Neighboring gene STARR-positive B cell enhancer ABC_E9166 Neighboring gene PHD finger protein 10 Neighboring gene dynein light chain Tctex-type 2A3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175173.3 → NP_780382.2  WD repeat-containing protein 27

    See identical proteins and their annotated locations for NP_780382.2

    Status: VALIDATED

    Source sequence(s)
    AK077050, AV277048
    Consensus CDS
    CCDS37443.1
    UniProtKB/Swiss-Prot
    Q8C5V5, Q8CA00
    Related
    ENSMUSP00000153717.2, ENSMUST00000228330.2
    Conserved Domains (3) summary
    COG2319
    Location:53 → 236
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    15005092..15163540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524929.5 → XP_006524992.1  WD repeat-containing protein 27 isoform X4

    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 811
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_011246612.4 → XP_011244914.1  WD repeat-containing protein 27 isoform X3

    See identical proteins and their annotated locations for XP_011244914.1

    UniProtKB/TrEMBL
    A0A338P6H6
    Related
    ENSMUSP00000155992.2, ENSMUST00000232147.2
    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 822
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_006524928.3 → XP_006524991.1  WD repeat-containing protein 27 isoform X3

    See identical proteins and their annotated locations for XP_006524991.1

    UniProtKB/TrEMBL
    A0A338P6H6
    Related
    ENSMUSP00000158649.2, ENSMUST00000238668.2
    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 822
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_017317639.1 → XP_017173128.1  WD repeat-containing protein 27 isoform X1

    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 813
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_017317640.3 → XP_017173129.1  WD repeat-containing protein 27 isoform X5

    Conserved Domains (2) summary
    sd00039
    Location:450 → 487
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:450 → 749
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_006524925.5 → XP_006524988.1  WD repeat-containing protein 27 isoform X1

    See identical proteins and their annotated locations for XP_006524988.1

    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 813
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  7. XM_006524926.5 → XP_006524989.1  WD repeat-containing protein 27 isoform X1

    See identical proteins and their annotated locations for XP_006524989.1

    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 813
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  8. XM_006524934.4 → XP_006524997.1  WD repeat-containing protein 27 isoform X8

    Conserved Domains (2) summary
    sd00039
    Location:278 → 315
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:278 → 577
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. XM_011246611.3 → XP_011244913.1  WD repeat-containing protein 27 isoform X2

    Conserved Domains (2) summary
    sd00039
    Location:514 → 551
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:514 → 811
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  10. XM_011246616.3 → XP_011244918.1  WD repeat-containing protein 27 isoform X7

    See identical proteins and their annotated locations for XP_011244918.1

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  11. XM_006524931.4 → XP_006524994.1  WD repeat-containing protein 27 isoform X6

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  12. XM_011246617.4 → XP_011244919.1  WD repeat-containing protein 27 isoform X7

    See identical proteins and their annotated locations for XP_011244919.1

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  13. XM_017317641.3 → XP_017173130.1  WD repeat-containing protein 27 isoform X9

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  14. XM_017317642.3 → XP_017173131.1  WD repeat-containing protein 27 isoform X10

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  15. XM_006524936.3 → XP_006524999.1  WD repeat-containing protein 27 isoform X11

    Conserved Domains (2) summary
    sd00039
    Location:73 → 118
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:47 → 235
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_001782112.3 RNA Sequence

  2. XR_003952182.2 RNA Sequence

  3. XR_004939577.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C5V5.2 GenPept UniProtKB/Swiss-Prot:Q8C5V5

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