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Rnf215 ring finger protein 215 [ Mus musculus (house mouse) ]

Gene ID: 71673, updated on 5-Mar-2024

Summary

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Official Symbol
Rnf215provided by MGI
Official Full Name
ring finger protein 215provided by MGI
Primary source
MGI:MGI:1918923
See related
Ensembl:ENSMUSG00000003581 AllianceGenome:MGI:1918923
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610009J22Rik
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Golgi to vacuole transport; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be part of Golgi transport complex. Predicted to be active in endosome; membrane; and trans-Golgi network. Orthologous to human RNF215 (ring finger protein 215). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 27.0), ovary adult (RPKM 20.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 A1; 11 2.89 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4085158..4091193)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4135157..4141193)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 2 Neighboring gene predicted gene, 51934 Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene microRNA 3060 Neighboring gene coiled-coil domain containing 157 Neighboring gene splicing factor 3a, subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E727 Neighboring gene TBC1 domain family, member 10a Neighboring gene STARR-positive B cell enhancer ABC_E2978 Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC106323, MGC144708, MGC144709

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RING finger protein 215

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363143.1 → NP_001350072.1  RING finger protein 215 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL807825
    Conserved Domains (1) summary
    cd16670
    Location:298 → 347
    RING-H2_RNF215; RING finger, H2 subclass, found in RING finger protein 215 (RNF215) and similar proteins

  2. NM_027859.3 → NP_082135.2  RING finger protein 215 isoform 1 precursor

    See identical proteins and their annotated locations for NP_082135.2

    Status: VALIDATED

    Source sequence(s)
    BC115907, BM120893, BM948157, CX203997
    Consensus CDS
    CCDS24378.1
    UniProtKB/Swiss-Prot
    Q5SPX2, Q5SPX3, Q5SPX4, Q9DCW1
    Related
    ENSMUSP00000003677.5, ENSMUST00000003677.11
    Conserved Domains (1) summary
    pfam13639
    Location:325 → 368
    zf-RING_2; Ring finger domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    4085158..4091193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003949509.2 RNA Sequence

  2. XR_380981.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SPX3.1 GenPept UniProtKB/Swiss-Prot:Q5SPX3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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