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Chst9 carbohydrate sulfotransferase 9 [ Mus musculus (house mouse) ]

Gene ID: 71367, updated on 11-Apr-2024

Summary

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Official Symbol
Chst9provided by MGI
Official Full Name
carbohydrate sulfotransferase 9provided by MGI
Primary source
MGI:MGI:1918617
See related
Ensembl:ENSMUSG00000047161 AllianceGenome:MGI:1918617
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GalNAc4ST-2; galNAc-4-ST2; 5430438D01Rik
Summary
Enables N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in proteoglycan biosynthetic process and sulfur compound metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Orthologous to human CHST9 (carbohydrate sulfotransferase 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
human all
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Genomic context

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Location:
18 A1; 18 8.85 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (15584830..15893214, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (15451773..15760157, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A830021F12 gene Neighboring gene aquaporin 4 Neighboring gene fibrillarin pseudogene Neighboring gene STARR-seq mESC enhancer starr_43888 Neighboring gene STARR-seq mESC enhancer starr_43889 Neighboring gene predicted gene, 30452 Neighboring gene STARR-seq mESC enhancer starr_43890 Neighboring gene STARR-seq mESC enhancer starr_43891 Neighboring gene STARR-seq mESC enhancer starr_43892 Neighboring gene STARR-seq mESC enhancer starr_43893 Neighboring gene predicted gene, 54036 Neighboring gene STARR-seq mESC enhancer starr_43895 Neighboring gene ribosomal protein L11 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl. Okuda T, et al. J Biochem, 2003 Jul. PMID 12944377
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC130338

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetylgalactosamine 4-O-sulfotransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables N-acetylgalactosamine 4-O-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sulfur compound metabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
carbohydrate sulfotransferase 9
Names
N-acetylgalactosamine-4-O-sulfotransferase 2
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
galNAc-4-O-sulfotransferase 2
NP_001351921.1
NP_951010.1
XP_017173481.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364992.1 → NP_001351921.1  carbohydrate sulfotransferase 9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102397, AK017407
    UniProtKB/TrEMBL
    Q3KNB9
    Conserved Domains (1) summary
    pfam03567
    Location:133 → 362
    Sulfotransfer_2; Sulfotransferase family

  2. NM_199055.3 → NP_951010.1  carbohydrate sulfotransferase 9 isoform 1

    See identical proteins and their annotated locations for NP_951010.1

    Status: VALIDATED

    Source sequence(s)
    AC102397, AC102416, AC157900
    Consensus CDS
    CCDS29074.1
    UniProtKB/Swiss-Prot
    Q76EC5
    UniProtKB/TrEMBL
    Q3KNB9
    Related
    ENSMUSP00000049975.7, ENSMUST00000053017.13
    Conserved Domains (1) summary
    pfam03567
    Location:179 → 408
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    15584830..15893214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317992.3 → XP_017173481.1  carbohydrate sulfotransferase 9 isoform X1

    UniProtKB/TrEMBL
    Q3KNB9
    Conserved Domains (1) summary
    pfam03567
    Location:115 → 344
    Sulfotransfer_2; Sulfotransferase family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q76EC5.1 GenPept UniProtKB/Swiss-Prot:Q76EC5

Gene LinkOut

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