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Noxred1 NADP+ dependent oxidoreductase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 71275, updated on 5-Mar-2024

Summary

Official Symbol
Noxred1provided by MGI
Official Full Name
NADP+ dependent oxidoreductase domain containing 1provided by MGI
Primary source
MGI:MGI:1918525
See related
Ensembl:ENSMUSG00000072919 AllianceGenome:MGI:1918525
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933437F05Rik
Summary
Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Orthologous to human NOXRED1 (NADP dependent oxidoreductase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 25.5) and CNS E14 (RPKM 1.2) See more
Orthologs
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Genomic context

See Noxred1 in Genome Data Viewer
Location:
12 D2; 12 41.42 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (87267897..87285375, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (87221123..87238601, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene glutathione transferase zeta 1 (maleylacetoacetate isomerase) Neighboring gene predicted gene 6566 Neighboring gene transmembrane p24 trafficking protein 8 Neighboring gene STARR-positive B cell enhancer ABC_E9041 Neighboring gene sterile alpha motif domain containing 15 Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene AHA1, activator of heat shock protein ATPase 1 Neighboring gene predicted gene, 53736

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Clone Names

  • MGC118344

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables pyrroline-5-carboxylate reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in L-proline biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
NADP-dependent oxidoreductase domain-containing protein 1
Names
pyrroline-5-carboxylate reductase-like protein C14orf148 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027744.1NP_082020.1  NADP-dependent oxidoreductase domain-containing protein 1

    See identical proteins and their annotated locations for NP_082020.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125331
    Consensus CDS
    CCDS36502.1
    UniProtKB/Swiss-Prot
    Q9D3S5
    Related
    ENSMUSP00000152486.2, ENSMUST00000222480.2
    Conserved Domains (1) summary
    cl21454
    Location:82160
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    87267897..87285375 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)