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Spats1 spermatogenesis associated, serine-rich 1 [ Mus musculus (house mouse) ]

Gene ID: 71020, updated on 21-Apr-2024

Summary

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Official Symbol
Spats1provided by MGI
Official Full Name
spermatogenesis associated, serine-rich 1provided by MGI
Primary source
MGI:MGI:1918270
See related
Ensembl:ENSMUSG00000023935 AllianceGenome:MGI:1918270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ddip; Srsp1; 1700011H05Rik; 4933400B06Rik
Summary
Is expressed in nervous system and testis. Orthologous to human SPATS1 (spermatogenesis associated serine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 3.7), frontal lobe adult (RPKM 0.6) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 B3; 17 22.44 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (45754156..45785864, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (45443230..45475108, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8677 Neighboring gene cell division cycle 5-like Neighboring gene RIKEN cDNA B230354K17 gene Neighboring gene STARR-positive B cell enhancer ABC_E5612 Neighboring gene STARR-seq mESC enhancer starr_42621 Neighboring gene STARR-seq mESC enhancer starr_42624 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:45625569-45626099 Neighboring gene STARR-seq mESC enhancer starr_42626 Neighboring gene STARR-positive B cell enhancer ABC_E4215 Neighboring gene STARR-positive B cell enhancer ABC_E9052 Neighboring gene alanyl-tRNA synthetase 2, mitochondrial Neighboring gene t-complex-associated testis expressed 1 Neighboring gene transmembrane protein 151B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. SPATS1 (spermatogenesis-associated, serine-rich 1) is not essential for spermatogenesis and fertility in mouse. Capoano CA, et al. PLoS One, 2021. PMID 33945571, Free PMC Article
  2. Identification and characterization of SRSP1, a rat gene differentially expressed during spermatogenesis and coding for a serine stretch-containing protein. Geisinger A, et al. Cytogenet Genome Res, 2002. PMID 12826748
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
spermatogenesis-associated serine-rich protein 1
Names
dvl2-DEP domain-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357831.1 → NP_001344760.1  spermatogenesis-associated serine-rich protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC163677
    Consensus CDS
    CCDS89103.1
    Related
    ENSMUSP00000156716.2, ENSMUST00000233553.2
    Conserved Domains (1) summary
    pfam15160
    Location:10 → 255
    SASRP1; Spermatogenesis-associated serine-rich protein 1

  2. NM_001357832.1 → NP_001344761.1  spermatogenesis-associated serine-rich protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC163677, AK005865, AK016586
    Consensus CDS
    CCDS89102.1
    Related
    ENSMUSP00000156469.2, ENSMUST00000233769.2
    Conserved Domains (1) summary
    pfam15160
    Location:10 → 234
    SASRP1; Spermatogenesis-associated serine-rich protein 1

  3. NM_027649.3 → NP_081925.2  spermatogenesis-associated serine-rich protein 1 isoform 1

    See identical proteins and their annotated locations for NP_081925.2

    Status: VALIDATED

    Source sequence(s)
    AK005865, AK016586, AV045867, BC131909
    Consensus CDS
    CCDS50118.1
    UniProtKB/Swiss-Prot
    A2RRY8, Q6VNB9, Q9CUD9, Q9DAG2
    Related
    ENSMUSP00000024731.9, ENSMUST00000024731.9
    Conserved Domains (1) summary
    pfam15160
    Location:10 → 255
    SASRP1; Spermatogenesis-associated serine-rich protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    45754156..45785864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160786.1 → XP_036016679.1  spermatogenesis-associated serine-rich protein 1 isoform X1

    Conserved Domains (1) summary
    pfam15160
    Location:10 → 234
    SASRP1; Spermatogenesis-associated serine-rich protein 1

  2. XM_011246605.3 → XP_011244907.1  spermatogenesis-associated serine-rich protein 1 isoform X2

    Conserved Domains (1) summary
    pfam15160
    Location:9 → 103
    SASRP1; Spermatogenesis-associated serine-rich protein 1

RNA

  1. XR_004939576.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2RRY8.1 GenPept UniProtKB/Swiss-Prot:A2RRY8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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