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4931406C07Rik RIKEN cDNA 4931406C07 gene [ Mus musculus (house mouse) ]

Gene ID: 70984, updated on 5-Mar-2024

Summary

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Official Symbol
4931406C07Rikprovided by MGI
Official Full Name
RIKEN cDNA 4931406C07 geneprovided by MGI
Primary source
MGI:MGI:1918234
See related
Ensembl:ENSMUSG00000031938 AllianceGenome:MGI:1918234
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Predicted to be located in nuclear body. Predicted to be active in nucleus. Is expressed in central nervous system; dorsal root ganglion; genitourinary system; neural retina; and nucleus pulposus. Orthologous to human C11orf54 (chromosome 11 open reading frame 54). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney adult (RPKM 50.7), subcutaneous fat pad adult (RPKM 17.4) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 A2; 9 4.76 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (15194633..15217836, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (15283337..15306448, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51702 Neighboring gene V-set and transmembrane domain containing 5 Neighboring gene mediator complex subunit 17 Neighboring gene STARR-seq mESC enhancer starr_23372 Neighboring gene STARR-positive B cell enhancer ABC_E6715 Neighboring gene TATA-box binding protein associated factor, RNA polymerase I, D Neighboring gene microRNA 7650 Neighboring gene predicted gene, 24455

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation. Chu R, et al. Mol Cell Biol, 2004 Jul. PMID 15226431, Free PMC Article
  2. Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Rutledge EA, et al. Development, 2017 Sep 1. PMID 28705898, Free PMC Article
  3. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  4. Mutagenesis of diploid mammalian genes by gene entrapment. Lin Q, et al. Nucleic Acids Res, 2006. PMID 17062627, Free PMC Article
  5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on ester bonds IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity, acting on ester bonds ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ester hydrolase C11orf54 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199484.1 → NP_001186413.1  ester hydrolase C11orf54 homolog isoform 1

    See identical proteins and their annotated locations for NP_001186413.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AC154296, AK133192, CK384052
    Consensus CDS
    CCDS22835.1
    UniProtKB/Swiss-Prot
    Q91V76
    Related
    ENSMUSP00000136717.2, ENSMUST00000180339.8
    Conserved Domains (1) summary
    cd17298
    Location:14 → 304
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

  2. NM_001199485.1 → NP_001186414.1  ester hydrolase C11orf54 homolog isoform 1

    See identical proteins and their annotated locations for NP_001186414.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has a different 5' UTR segment, compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AK016432, AK147073, BY118027, CK384052
    Consensus CDS
    CCDS22835.1
    UniProtKB/Swiss-Prot
    Q91V76
    Related
    ENSMUSP00000136335.2, ENSMUST00000178977.9
    Conserved Domains (1) summary
    cd17298
    Location:14 → 304
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

  3. NM_001359258.1 → NP_001346187.1  ester hydrolase C11orf54 homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame exon in the coding region, compared to variant 1. This variant encodes a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC154296
    Consensus CDS
    CCDS90500.1
    UniProtKB/TrEMBL
    A0A1L1SSF8
    Related
    ENSMUSP00000149878.2, ENSMUST00000216955.2
    Conserved Domains (1) summary
    cd17298
    Location:8 → 271
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

  4. NM_133732.3 → NP_598493.1  ester hydrolase C11orf54 homolog isoform 1

    See identical proteins and their annotated locations for NP_598493.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has a different 5' UTR segment, compared to variant 1. Variants 1, 2, and 3 encode the same protein.
    Source sequence(s)
    AC154296, AK133192, CK384052, CT010296
    Consensus CDS
    CCDS22835.1
    UniProtKB/Swiss-Prot
    Q91V76
    Related
    ENSMUSP00000034414.9, ENSMUST00000034414.10
    Conserved Domains (1) summary
    cd17298
    Location:14 → 304
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    15194633..15217836 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155283.1 → XP_036011176.1  ester hydrolase C11orf54 homolog isoform X2

    UniProtKB/TrEMBL
    A0A1L1SSF8
    Conserved Domains (1) summary
    cd17298
    Location:8 → 271
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012

  2. XM_030244585.2 → XP_030100445.1  ester hydrolase C11orf54 homolog isoform X3

    Conserved Domains (1) summary
    pfam08925
    Location:1 → 192
    DUF1907; Domain of Unknown Function (DUF1907)

  3. XM_006510596.3 → XP_006510659.1  ester hydrolase C11orf54 homolog isoform X1

    See identical proteins and their annotated locations for XP_006510659.1

    UniProtKB/Swiss-Prot
    Q91V76
    Conserved Domains (1) summary
    cd17298
    Location:14 → 304
    DUF1907; proteins similar to putative ester hydrolase C11orf54/PTD012
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91V76.1 GenPept UniProtKB/Swiss-Prot:Q91V76

Gene LinkOut

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