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Spata1 spermatogenesis associated 1 [ Mus musculus (house mouse) ]

Gene ID: 70951, updated on 5-Mar-2024

Summary

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Official Symbol
Spata1provided by MGI
Official Full Name
spermatogenesis associated 1provided by MGI
Primary source
MGI:MGI:1918201
See related
Ensembl:ENSMUSG00000028188 AllianceGenome:MGI:1918201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SP-2; 4921536I21Rik
Summary
Orthologous to human SPATA1 (spermatogenesis associated 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 21.9), CNS E11.5 (RPKM 1.2) and 1 other tissue See more
Orthologs
human all
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Genomic context

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Location:
3 H2; 3 71.3 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (146162955..146205548, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (146457202..146499793, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22078 Neighboring gene SSX family member 2 interacting protein Neighboring gene STARR-positive B cell enhancer ABC_E9230 Neighboring gene chitobiase Neighboring gene STARR-positive B cell enhancer ABC_E6144 Neighboring gene G protein subunit gamma 5 Neighboring gene STARR-positive B cell enhancer ABC_E11229 Neighboring gene ribosome production factor 1 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein. Zhang L, et al. Dev Dyn, 2020 Apr. PMID 31816150, Free PMC Article
  2. Disruption of G-protein γ5 subtype causes embryonic lethality in mice. Moon AM, et al. PLoS One, 2014. PMID 24599258, Free PMC Article
  3. Centimorgan-range one-step mapping of fertility traits using interspecific recombinant congenic mice. L'Hôte D, et al. Genetics, 2007 Jul. PMID 17483418, Free PMC Article
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein.
    Title: Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
NOT located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
spermatogenesis-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001316756.2 → NP_001303685.1  spermatogenesis-associated protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC124987, AC141632
    Consensus CDS
    CCDS38666.1
    UniProtKB/Swiss-Prot
    B9EI96, Q7TPN4, Q9D5R4
    Related
    ENSMUSP00000142800.2, ENSMUST00000197980.5
    Conserved Domains (1) summary
    pfam15743
    Location:279 → 428
    SPATA1_C; Spermatogenesis-associated C-terminus

  2. NM_001370604.1 → NP_001357533.1  spermatogenesis-associated protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC124987, AC141632
    Conserved Domains (1) summary
    pfam15743
    Location:276 → 386
    SPATA1_C; Spermatogenesis-associated C-terminus

  3. NM_027617.3 → NP_081893.1  spermatogenesis-associated protein 1 isoform 1

    See identical proteins and their annotated locations for NP_081893.1

    Status: VALIDATED

    Source sequence(s)
    AC124987, AC141632
    Consensus CDS
    CCDS38666.1
    UniProtKB/Swiss-Prot
    B9EI96, Q7TPN4, Q9D5R4
    Related
    ENSMUSP00000029839.5, ENSMUST00000029839.11
    Conserved Domains (1) summary
    pfam15743
    Location:279 → 428
    SPATA1_C; Spermatogenesis-associated C-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    146162955..146205548 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163322.1 → XP_036019215.1  spermatogenesis-associated protein 1 isoform X5

    Conserved Domains (1) summary
    pfam15743
    Location:233 → 365
    SPATA1_C; Spermatogenesis-associated C-terminus

  2. XM_036163320.1 → XP_036019213.1  spermatogenesis-associated protein 1 isoform X3

    Conserved Domains (1) summary
    pfam15743
    Location:259 → 407
    SPATA1_C; Spermatogenesis-associated C-terminus

  3. XM_036163323.1 → XP_036019216.1  spermatogenesis-associated protein 1 isoform X6

    Conserved Domains (1) summary
    pfam15743
    Location:276 → 353
    SPATA1_C; Spermatogenesis-associated C-terminus

  4. XM_036163321.1 → XP_036019214.1  spermatogenesis-associated protein 1 isoform X4

    Conserved Domains (1) summary
    pfam15743
    Location:280 → 395
    SPATA1_C; Spermatogenesis-associated C-terminus

  5. XM_036163317.1 → XP_036019210.1  spermatogenesis-associated protein 1 isoform X2

    Conserved Domains (1) summary
    pfam15743
    Location:280 → 408
    SPATA1_C; Spermatogenesis-associated C-terminus

  6. XM_036163318.1 → XP_036019211.1  spermatogenesis-associated protein 1 isoform X2

    Conserved Domains (1) summary
    pfam15743
    Location:280 → 408
    SPATA1_C; Spermatogenesis-associated C-terminus

  7. XM_036163319.1 → XP_036019212.1  spermatogenesis-associated protein 1 isoform X2

    Conserved Domains (1) summary
    pfam15743
    Location:280 → 408
    SPATA1_C; Spermatogenesis-associated C-terminus

  8. XM_006502090.5 → XP_006502153.1  spermatogenesis-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006502153.1

    UniProtKB/Swiss-Prot
    B9EI96, Q7TPN4, Q9D5R4
    Conserved Domains (1) summary
    pfam15743
    Location:279 → 428
    SPATA1_C; Spermatogenesis-associated C-terminus

  9. XM_036163324.1 → XP_036019217.1  spermatogenesis-associated protein 1 isoform X7

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D5R4.1 GenPept UniProtKB/Swiss-Prot:Q9D5R4

Gene LinkOut

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