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Lrrc63 leucine rich repeat containing 63 [ Mus musculus (house mouse) ]

Gene ID: 70859, updated on 5-Mar-2024

Summary

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Official Symbol
Lrrc63provided by MGI
Official Full Name
leucine rich repeat containing 63provided by MGI
Primary source
MGI:MGI:1918109
See related
Ensembl:ENSMUSG00000021997 AllianceGenome:MGI:1918109
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4921509B22Rik
Summary
Orthologous to human LRRC63 (leucine rich repeat containing 63). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 17.3) See more
Orthologs
human all
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Genomic context

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See Lrrc63 in Genome Data Viewer
Location:
14 D3; 14 39.59 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (75321743..75368402, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (75084303..75130962, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37134 Neighboring gene predicted gene 4278 Neighboring gene STARR-positive B cell enhancer ABC_E10834 Neighboring gene STARR-positive B cell enhancer ABC_E757 Neighboring gene RUN and cysteine rich domain containing beclin 1 interacting protein like Neighboring gene predicted gene, 57618 Neighboring gene STARR-positive B cell enhancer mm9_chr14:75456661-75456962 Neighboring gene STARR-positive B cell enhancer mm9_chr14:75460374-75460674 Neighboring gene STARR-seq mESC enhancer starr_37135 Neighboring gene predicted gene 15628 Neighboring gene lymphocyte cytosolic protein 1 Neighboring gene STARR-positive B cell enhancer mm9_chr14:75576489-75576789 Neighboring gene STARR-seq mESC enhancer starr_37136 Neighboring gene STARR-positive B cell enhancer ABC_E4120 Neighboring gene STARR-positive B cell enhancer ABC_E8899 Neighboring gene STARR-positive B cell enhancer ABC_E7338 Neighboring gene carboxypeptidase B2 Neighboring gene predicted gene, 35679 Neighboring gene ribosomal protein L17 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 63

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001404637.1 → NP_001391566.1  leucine-rich repeat-containing protein 63

    Status: VALIDATED

    Source sequence(s)
    AC129591
    UniProtKB/Swiss-Prot
    A6H694, G3X8V0, Q9D5X5

  2. NM_027581.2 → NP_081857.1  leucine-rich repeat-containing protein 63

    See identical proteins and their annotated locations for NP_081857.1

    Status: VALIDATED

    Source sequence(s)
    AC129591
    Consensus CDS
    CCDS49539.1
    UniProtKB/Swiss-Prot
    A6H694, G3X8V0, Q9D5X5
    Related
    ENSMUSP00000022574.4, ENSMUST00000022574.5
    Conserved Domains (2) summary
    COG4886
    Location:383 → 513
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:392 → 414
    LRR_RI; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    75321743..75368402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519546.1 → XP_006519609.1  leucine-rich repeat-containing protein 63 isoform X1

    See identical proteins and their annotated locations for XP_006519609.1

    UniProtKB/Swiss-Prot
    A6H694, G3X8V0, Q9D5X5
    Conserved Domains (2) summary
    COG4886
    Location:383 → 513
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:392 → 414
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_006519548.2 → XP_006519611.1  leucine-rich repeat-containing protein 63 isoform X3

  3. XM_017316193.2 → XP_017171682.1  leucine-rich repeat-containing protein 63 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6H694.2 GenPept UniProtKB/Swiss-Prot:A6H694

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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