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Spag9 sperm associated antigen 9 [ Mus musculus (house mouse) ]

Gene ID: 70834, updated on 8-May-2024

Summary

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Official Symbol
Spag9provided by MGI
Official Full Name
sperm associated antigen 9provided by MGI
Primary source
MGI:MGI:1918084
See related
Ensembl:ENSMUSG00000020859 AllianceGenome:MGI:1918084
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
JLP; Jip4; syd1; JIP-4; JSAP2; JSAP2a; Mapk8ip4; 3110018C07Rik; 4733401I23Rik; 4831406C20Rik
Summary
Enables several functions, including MAP-kinase scaffold activity; kinesin binding activity; and protein kinase binding activity. Acts upstream of or within several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron differentiation. Located in perinuclear region of cytoplasm. Is expressed in central nervous system; dorsal root ganglion; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 26.0), cerebellum adult (RPKM 26.0) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 58.9 cM
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (93886794..94016919)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (93996046..94126093)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1144 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:93829571-93829796 Neighboring gene NME/NM23 nucleoside diphosphate kinase 2 Neighboring gene STARR-seq mESC enhancer starr_30446 Neighboring gene predicted gene, 35198 Neighboring gene NME/NM23 nucleoside diphosphate kinase 1 Neighboring gene STARR-seq mESC enhancer starr_30447 Neighboring gene ribosomal protein L27 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5269 Neighboring gene STARR-seq mESC enhancer starr_30448 Neighboring gene STARR-seq mESC enhancer starr_30449 Neighboring gene predicted gene, 38951 Neighboring gene STARR-positive B cell enhancer ABC_E10706 Neighboring gene RIKEN cDNA B230206L02 gene Neighboring gene STARR-seq mESC enhancer starr_30450 Neighboring gene STARR-seq mESC enhancer starr_30451 Neighboring gene predicted gene, 35338 Neighboring gene VISTA enhancer mm1496 Neighboring gene STARR-seq mESC enhancer starr_30458 Neighboring gene STARR-positive B cell enhancer mm9_chr11:94071474-94071775 Neighboring gene STARR-positive B cell enhancer ABC_E467 Neighboring gene transducer of ErbB-2.1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Scaffold protein JLP mediates TCR-initiated CD4(+)T cell activation and CD154 expression. Yan Q, et al. Mol Immunol, 2017 Jul. PMID 28521278
  2. The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice. Enkhtuya R, et al. Genes Cells, 2014 Apr. PMID 24520900
  3. Ablation of the scaffold protein JLP causes reduced fertility in male mice. Iwanaga A, et al. Transgenic Res, 2008 Dec. PMID 18574703
  4. Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice. Hanata N, et al. Front Immunol, 2020. PMID 32655553, Free PMC Article
  5. A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis. Yan Q, et al. Commun Biol, 2020 Jun 5. PMID 32504044, Free PMC Article

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A negative feedback loop between JNK-associated leucine zipper protein and TGF-beta1 regulates kidney fibrosis.
    Title: A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis.
  2. JLP-deficiency impaired T-cell proliferation.
    Title: Scaffold protein JLP mediates TCR-initiated CD4(+)T cell activation and CD154 expression.
  3. data establish JSAP1 and JLP as positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration.
    Title: JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
  4. JSAP1 and JLP play critical roles in kinesin-1-dependent axonal transport
    Title: Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.
  5. JSAP1 and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 localization to the midbody by forming a tripartite complex of JSAP1/JLP, active ARF6, and kinesin-1.
    Title: JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.
  6. JLP in skin basal keratinocytes plays an important role in UVB-induced apoptosis by modulating p38 MAPK signaling pathways.
    Title: The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice.
  7. Data indicate a role of a scaffolding protein JLP in the regulation of surface CD40 expression and fine-tuning of dendritic cell (DC) function.
    Title: A novel role of the scaffolding protein JLP in tuning CD40-induced activation of dendritic cells.
  8. A functional role for JLP in the gep oncogene-regulated neoplastic signaling pathway.
    Title: Neoplastic transformation induced by the gep oncogenes involves the scaffold protein JNK-interacting leucine zipper protein.
  9. Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
    Title: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
  10. Ablation of the scaffold protein JLP causes reduced fertility in male mice.
    Title: Ablation of the scaffold protein JLP causes reduced fertility in male mice.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (2) 
  • Chemically induced (ENU) (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables JUN kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables JUN kinase binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables MAP-kinase scaffold activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables MAP-kinase scaffold activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables kinesin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinesin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor complex adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lysosome localization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of dendrite extension ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within positive regulation of MAPK cascade IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of MAPK cascade IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within striated muscle cell differentiation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
C-Jun-amino-terminal kinase-interacting protein 4
Names
JNK-associated leucine-zipper protein
JNK-interacting leucine zipper
JNK-interacting protein 4
JNK/SAPK-associated protein 2
mitogen-activated protein kinase 8-interacting protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025428.2 → NP_001020599.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK014060, BC052058, BC094670, CJ123181, CK781075, CO044222
    Consensus CDS
    CCDS36282.1
    UniProtKB/TrEMBL
    E9PUD1, F8WH31
    Related
    ENSMUSP00000090452.5, ENSMUST00000092777.11
    Conserved Domains (2) summary
    pfam15898
    Location:301 → 400
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:254 → 322
    JIP_LZII; JNK-interacting protein leucine zipper II

  2. NM_001025429.2 → NP_001020600.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK014060, AK172961, BC094670, CJ123181, CO044222
    Consensus CDS
    CCDS56797.1
    UniProtKB/TrEMBL
    F8WH31
    Related
    ENSMUSP00000075115.7, ENSMUST00000075695.13
    Conserved Domains (2) summary
    pfam15898
    Location:300 → 399
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:253 → 321
    JIP_LZII; JNK-interacting protein leucine zipper II

  3. NM_001025430.2 → NP_001020601.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 4

    See identical proteins and their annotated locations for NP_001020601.1

    Status: VALIDATED

    Source sequence(s)
    AK014060, BC094670, CJ123181, CO044222
    Consensus CDS
    CCDS25249.1
    UniProtKB/TrEMBL
    A0A0R4J196, F8WH31
    Related
    ENSMUSP00000099457.4, ENSMUST00000103168.10
    Conserved Domains (2) summary
    pfam15898
    Location:296 → 395
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:249 → 317
    JIP_LZII; JNK-interacting protein leucine zipper II

  4. NM_001199203.2 → NP_001186132.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AB047782, AK147431, AK161623, AL662838, CO044222
    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    pfam07926
    Location:56 → 162
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam15898
    Location:453 → 552
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:406 → 474
    JIP_LZII; JNK-interacting protein leucine zipper II

  5. NM_001199204.2 → NP_001186133.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 6

    See identical proteins and their annotated locations for NP_001186133.1

    Status: VALIDATED

    Source sequence(s)
    AK147431, AK161623, CO044222, FJ042496
    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    UniProtKB/TrEMBL
    B8X349
    Conserved Domains (4) summary
    pfam07926
    Location:56 → 162
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam15898
    Location:439 → 538
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:392 → 460
    JIP_LZII; JNK-interacting protein leucine zipper II

  6. NM_001199205.2 → NP_001186134.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AK147431, BC060100, CJ123181, CO044222
    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (2) summary
    pfam15898
    Location:296 → 395
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:249 → 317
    JIP_LZII; JNK-interacting protein leucine zipper II

  7. NM_001363157.1 → NP_001350086.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AL662838
    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (3) summary
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:396 → 464
    JIP_LZII; JNK-interacting protein leucine zipper II
    cl25732
    Location:33 → 520
    SMC_N; RecF/RecN/SMC N terminal domain

  8. NM_027569.3 → NP_081845.2  C-Jun-amino-terminal kinase-interacting protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AF327451, AK030165, AK172961, BB618351, BC060506, BC094670, CO044222
    Consensus CDS
    CCDS25248.1
    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Related
    ENSMUSP00000042271.8, ENSMUST00000041956.14
    Conserved Domains (4) summary
    pfam07926
    Location:56 → 162
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam15898
    Location:439 → 538
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam16471
    Location:392 → 460
    JIP_LZII; JNK-interacting protein leucine zipper II

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    93886794..94016919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534210.5 → XP_006534273.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006534273.1

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 539
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:415 → 483
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:458 → 651
    DUF5401; Family of unknown function (DUF5401)

  2. XM_006534214.5 → XP_006534277.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X5

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 539
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:415 → 483
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:458 → 651
    DUF5401; Family of unknown function (DUF5401)

  3. XM_006534212.5 → XP_006534275.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X3

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 534
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:410 → 478
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:453 → 646
    DUF5401; Family of unknown function (DUF5401)

  4. XM_006534211.5 → XP_006534274.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X2

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 535
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:411 → 479
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:454 → 647
    DUF5401; Family of unknown function (DUF5401)

  5. XM_006534213.5 → XP_006534276.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X4

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 530
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:406 → 474
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:449 → 642
    DUF5401; Family of unknown function (DUF5401)

  6. XM_006534215.5 → XP_006534278.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X6

    UniProtKB/Swiss-Prot
    Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
    Conserved Domains (4) summary
    COG0419
    Location:22 → 525
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam09744
    Location:25 → 178
    Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
    pfam16471
    Location:401 → 469
    JIP_LZII; JNK-interacting protein leucine zipper II
    pfam17380
    Location:444 → 637
    DUF5401; Family of unknown function (DUF5401)

  7. XM_030246314.2 → XP_030102174.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X11

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (2) summary
    COG1196
    Location:252 → 398
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16471
    Location:250 → 318
    JIP_LZII; JNK-interacting protein leucine zipper II

  8. XM_030246315.2 → XP_030102175.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X12

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:238 → 384
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:129 → 316
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:236 → 304
    JIP_LZII; JNK-interacting protein leucine zipper II

  9. XM_030246317.2 → XP_030102177.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X13

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:229 → 375
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:129 → 307
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:227 → 295
    JIP_LZII; JNK-interacting protein leucine zipper II

  10. XM_030246318.2 → XP_030102178.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X14

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:229 → 375
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:129 → 307
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:227 → 295
    JIP_LZII; JNK-interacting protein leucine zipper II

  11. XM_006534216.5 → XP_006534279.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X7

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:274 → 420
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:165 → 352
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:272 → 340
    JIP_LZII; JNK-interacting protein leucine zipper II

  12. XM_030246313.2 → XP_030102173.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X8

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:265 → 411
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:165 → 343
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:263 → 331
    JIP_LZII; JNK-interacting protein leucine zipper II

  13. XM_006534217.5 → XP_006534280.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X9

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (3) summary
    COG1196
    Location:260 → 406
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:151 → 338
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam16471
    Location:258 → 326
    JIP_LZII; JNK-interacting protein leucine zipper II

  14. XM_006534218.5 → XP_006534281.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X10

    UniProtKB/TrEMBL
    F8WH31
    Conserved Domains (2) summary
    COG1196
    Location:220 → 401
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam16471
    Location:253 → 321
    JIP_LZII; JNK-interacting protein leucine zipper II
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q58A65.2 GenPept UniProtKB/Swiss-Prot:Q58A65

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