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Spmip4 sperm microtubule inner protein 4 [ Mus musculus (house mouse) ]

Gene ID: 70821, updated on 3-Apr-2024

Summary

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Official Symbol
Spmip4provided by MGI
Official Full Name
sperm microtubule inner protein 4provided by MGI
Primary source
MGI:MGI:1918071
See related
Ensembl:ENSMUSG00000029828 AllianceGenome:MGI:1918071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TISP74; 4921507P07Rik
Summary
Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in centrosome. Orthologous to human C7orf31 (chromosome 7 open reading frame 31). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 82.5) See more
Orthologs
human all
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Genomic context

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Location:
6 B2.3; 6 24.32 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (50550282..50573847, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (50573302..50596852, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5430402O13 gene Neighboring gene cytochrome c, somatic Neighboring gene microRNA 6371 Neighboring gene STARR-positive B cell enhancer ABC_E3655 Neighboring gene predicted gene, 38807 Neighboring gene STARR-seq mESC enhancer starr_15852 Neighboring gene Crn, crooked neck-like 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†. Sun J, et al. Biol Reprod, 2020 Aug 4. PMID 32588039, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sperm-associated microtubule inner protein 4
Names
sperm associated microtubule inner protein 4
uncharacterized protein C7orf31 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417718.1 → NP_001404647.1  sperm-associated microtubule inner protein 4

    Status: VALIDATED

    Source sequence(s)
    AC153386
    UniProtKB/Swiss-Prot
    Q8K4U1, Q9D5Y0

  2. NM_027564.4 → NP_081840.1  sperm-associated microtubule inner protein 4

    See identical proteins and their annotated locations for NP_081840.1

    Status: VALIDATED

    Source sequence(s)
    AC153386
    Consensus CDS
    CCDS20132.1
    UniProtKB/Swiss-Prot
    Q8K4U1, Q9D5Y0
    UniProtKB/TrEMBL
    Q3TT91
    Related
    ENSMUSP00000031852.5, ENSMUST00000031852.5
    Conserved Domains (1) summary
    pfam15093
    Location:1 → 283
    DUF4555; Domain of unknown function (DUF4555)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    50550282..50573847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152303.1 → XP_036008196.1  sperm-associated microtubule inner protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q8K4U1, Q9D5Y0
    UniProtKB/TrEMBL
    Q3TT91
    Conserved Domains (1) summary
    pfam15093
    Location:1 → 283
    DUF4555; Domain of unknown function (DUF4555)

  2. XM_006506605.1 → XP_006506668.1  sperm-associated microtubule inner protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006506668.1

    UniProtKB/Swiss-Prot
    Q8K4U1, Q9D5Y0
    UniProtKB/TrEMBL
    Q3TT91
    Conserved Domains (1) summary
    pfam15093
    Location:1 → 283
    DUF4555; Domain of unknown function (DUF4555)

  3. XM_006506606.5 → XP_006506669.1  sperm-associated microtubule inner protein 4 isoform X2

    Conserved Domains (1) summary
    pfam15093
    Location:1 → 283
    DUF4555; Domain of unknown function (DUF4555)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D5Y0.1 GenPept UniProtKB/Swiss-Prot:Q9D5Y0

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