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Ankrd24 ankyrin repeat domain 24 [ Mus musculus (house mouse) ]

Gene ID: 70615, updated on 11-Apr-2024

Summary

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Official Symbol
Ankrd24provided by MGI
Official Full Name
ankyrin repeat domain 24provided by MGI
Primary source
MGI:MGI:1890394
See related
Ensembl:ENSMUSG00000054708 AllianceGenome:MGI:1890394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D10Bur2e; 4631433D01Rik; 5730519E19Rik
Summary
Is expressed in cochlea; olfactory epithelium; pituitary gland; vagus ganglion; and vestibulo-cochlear ganglion. Orthologous to human ANKRD24 (ankyrin repeat domain 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 10.1), CNS E18 (RPKM 9.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 C1; 10 39.72 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81464352..81483446)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81627821..81647612)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E464 Neighboring gene zinc finger protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_27345 Neighboring gene STARR-positive B cell enhancer ABC_E6888 Neighboring gene sirtuin 6 Neighboring gene STARR-positive B cell enhancer ABC_E9797 Neighboring gene STARR-positive B cell enhancer ABC_E6889 Neighboring gene STARR-seq mESC enhancer starr_27348 Neighboring gene predicted gene 10778 Neighboring gene predicted gene, 51792 Neighboring gene predicted gene 8112

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points. Krey JF, et al. J Cell Biol, 2022 Apr 4. PMID 35175278, Free PMC Article
  2. Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints. Puttagunta R, et al. Genome Res, 2000 Sep. PMID 10984455, Free PMC Article
  3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  4. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points.
    Title: ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in auditory receptor cell stereocilium organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in biological_process ND
No biological Data available
more info
  
involved_in sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in stereocilium IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374016.1 → NP_001360945.1  ankyrin repeat domain-containing protein 24 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC153919
    Conserved Domains (6) summary
    PTZ00322
    Location:190 → 311
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:56 → 243
    PHA02875; ankyrin repeat protein; Provisional
    COG1196
    Location:319 → 538
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:325 → 985
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:116 → 146
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:120 → 212
    Ank_2; Ankyrin repeats (3 copies)

  2. NM_027480.3 → NP_081756.4  ankyrin repeat domain-containing protein 24 isoform 2

    See identical proteins and their annotated locations for NP_081756.4

    Status: VALIDATED

    Source sequence(s)
    AC153919, AK043638, BC017633, CB524981, CJ177454, CJ183294, CJ243196
    Consensus CDS
    CCDS36001.1
    UniProtKB/Swiss-Prot
    E9QJV7, Q80VM7
    Related
    ENSMUSP00000112932.2, ENSMUST00000119336.8
    Conserved Domains (6) summary
    PTZ00322
    Location:160 → 281
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:26 → 213
    PHA02875; ankyrin repeat protein; Provisional
    COG1196
    Location:289 → 508
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:295 → 955
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:86 → 116
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    81464352..81483446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514093.5 → XP_006514156.1  ankyrin repeat domain-containing protein 24 isoform X3

    See identical proteins and their annotated locations for XP_006514156.1

    Conserved Domains (5) summary
    PTZ00322
    Location:189 → 310
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:55 → 242
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:324 → 1024
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:119 → 211
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_030245274.2 → XP_030101134.1  ankyrin repeat domain-containing protein 24 isoform X14

    UniProtKB/TrEMBL
    Q8VD21
    Conserved Domains (1) summary
    TIGR02168
    Location:384 → 566
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_006514096.5 → XP_006514159.1  ankyrin repeat domain-containing protein 24 isoform X5

    Conserved Domains (5) summary
    PTZ00322
    Location:160 → 281
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:26 → 213
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:295 → 995
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:86 → 116
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_006514098.5 → XP_006514161.1  ankyrin repeat domain-containing protein 24 isoform X7

    See identical proteins and their annotated locations for XP_006514161.1

    UniProtKB/Swiss-Prot
    E9QJV7, Q80VM7
    Conserved Domains (6) summary
    PTZ00322
    Location:160 → 281
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:26 → 213
    PHA02875; ankyrin repeat protein; Provisional
    COG1196
    Location:289 → 508
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:295 → 955
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:86 → 116
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:90 → 182
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_006514102.5 → XP_006514165.1  ankyrin repeat domain-containing protein 24 isoform X10

    See identical proteins and their annotated locations for XP_006514165.1

    Conserved Domains (4) summary
    PTZ00322
    Location:65 → 186
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:200 → 900
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:23 → 54
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:28 → 120
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_006514094.5 → XP_006514157.1  ankyrin repeat domain-containing protein 24 isoform X3

    See identical proteins and their annotated locations for XP_006514157.1

    Conserved Domains (5) summary
    PTZ00322
    Location:189 → 310
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:55 → 242
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:324 → 1024
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:119 → 211
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_036156008.1 → XP_036011901.1  ankyrin repeat domain-containing protein 24 isoform X8

    Conserved Domains (4) summary
    TIGR02168
    Location:234 → 934
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:25 → 55
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 45
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:29 → 121
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_036156013.1 → XP_036011906.1  ankyrin repeat domain-containing protein 24 isoform X12

    Conserved Domains (4) summary
    PTZ00322
    Location:16 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:151 → 851
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:7 → 38
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:1 → 71
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_006514103.5 → XP_006514166.1  ankyrin repeat domain-containing protein 24 isoform X10

    See identical proteins and their annotated locations for XP_006514166.1

    Conserved Domains (4) summary
    PTZ00322
    Location:65 → 186
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:200 → 900
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:23 → 54
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:28 → 120
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_006514091.5 → XP_006514154.1  ankyrin repeat domain-containing protein 24 isoform X1

    Conserved Domains (5) summary
    PTZ00322
    Location:207 → 328
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:73 → 260
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:342 → 1042
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:133 → 163
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:137 → 229
    Ank_2; Ankyrin repeats (3 copies)

  11. XM_006514097.5 → XP_006514160.1  ankyrin repeat domain-containing protein 24 isoform X6

    Conserved Domains (6) summary
    PTZ00322
    Location:207 → 328
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:73 → 260
    PHA02875; ankyrin repeat protein; Provisional
    COG1196
    Location:336 → 555
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:342 → 1002
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:133 → 163
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:137 → 229
    Ank_2; Ankyrin repeats (3 copies)

  12. XM_006514092.5 → XP_006514155.1  ankyrin repeat domain-containing protein 24 isoform X2

    Conserved Domains (5) summary
    PTZ00322
    Location:190 → 311
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:56 → 243
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:325 → 1025
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:116 → 146
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:120 → 212
    Ank_2; Ankyrin repeats (3 copies)

  13. XM_006514095.5 → XP_006514158.1  ankyrin repeat domain-containing protein 24 isoform X4

    Conserved Domains (5) summary
    PTZ00322
    Location:161 → 282
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:27 → 214
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:296 → 996
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:87 → 117
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:91 → 183
    Ank_2; Ankyrin repeats (3 copies)

  14. XM_006514099.5 → XP_006514162.1  ankyrin repeat domain-containing protein 24 isoform X8

    See identical proteins and their annotated locations for XP_006514162.1

    Conserved Domains (4) summary
    TIGR02168
    Location:234 → 934
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:25 → 55
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 45
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:29 → 121
    Ank_2; Ankyrin repeats (3 copies)

  15. XM_006514101.5 → XP_006514164.1  ankyrin repeat domain-containing protein 24 isoform X9

    Conserved Domains (4) summary
    PTZ00322
    Location:66 → 187
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:201 → 901
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:24 → 55
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:29 → 121
    Ank_2; Ankyrin repeats (3 copies)

  16. XM_036156009.1 → XP_036011902.1  ankyrin repeat domain-containing protein 24 isoform X11

    Conserved Domains (4) summary
    PTZ00322
    Location:56 → 177
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:191 → 891
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:14 → 45
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:19 → 111
    Ank_2; Ankyrin repeats (3 copies)

  17. XM_036156010.1 → XP_036011903.1  ankyrin repeat domain-containing protein 24 isoform X12

    Conserved Domains (4) summary
    PTZ00322
    Location:16 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:151 → 851
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:7 → 38
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:1 → 71
    Ank_2; Ankyrin repeats (3 copies)

  18. XM_036156011.1 → XP_036011904.1  ankyrin repeat domain-containing protein 24 isoform X12

    Conserved Domains (4) summary
    PTZ00322
    Location:16 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:151 → 851
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:7 → 38
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:1 → 71
    Ank_2; Ankyrin repeats (3 copies)

  19. XM_036156012.1 → XP_036011905.1  ankyrin repeat domain-containing protein 24 isoform X12

    Conserved Domains (4) summary
    PTZ00322
    Location:16 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:151 → 851
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:7 → 38
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:1 → 71
    Ank_2; Ankyrin repeats (3 copies)

  20. XM_006514104.5 → XP_006514167.1  ankyrin repeat domain-containing protein 24 isoform X12

    Conserved Domains (4) summary
    PTZ00322
    Location:16 → 137
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:151 → 851
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:7 → 38
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:1 → 71
    Ank_2; Ankyrin repeats (3 copies)

  21. XM_030245275.1 → XP_030101135.1  ankyrin repeat domain-containing protein 24 isoform X14

    UniProtKB/TrEMBL
    Q8VD21
    Conserved Domains (1) summary
    TIGR02168
    Location:384 → 566
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  22. XM_011243569.1 → XP_011241871.1  ankyrin repeat domain-containing protein 24 isoform X11

    Conserved Domains (4) summary
    PTZ00322
    Location:56 → 177
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    TIGR02168
    Location:191 → 891
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:14 → 45
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:19 → 111
    Ank_2; Ankyrin repeats (3 copies)

  23. XM_017314088.1 → XP_017169577.1  ankyrin repeat domain-containing protein 24 isoform X13

    UniProtKB/TrEMBL
    Q8VD21
    Conserved Domains (2) summary
    TIGR02168
    Location:485 → 667
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:23 → 174
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  24. XM_030245273.1 → XP_030101133.1  ankyrin repeat domain-containing protein 24 isoform X13

    UniProtKB/TrEMBL
    Q8VD21
    Conserved Domains (2) summary
    TIGR02168
    Location:485 → 667
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:23 → 174
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80VM7.4 GenPept UniProtKB/Swiss-Prot:Q80VM7

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