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Mospd1 motile sperm domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 70380, updated on 5-Mar-2024

Summary

Official Symbol
Mospd1provided by MGI
Official Full Name
motile sperm domain containing 1provided by MGI
Primary source
MGI:MGI:1917630
See related
Ensembl:ENSMUSG00000023074 AllianceGenome:MGI:1917630
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810018L05Rik
Summary
Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including brain; cranial ganglion; limb mesenchyme; tongue muscle; and vertebral axis musculature. Orthologous to human MOSPD1 (motile sperm domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 12.9), liver E14 (RPKM 6.9) and 19 other tissues See more
Orthologs
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Genomic context

Location:
X A5; X 29.51 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (52433471..52459567, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (53344594..53370658, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene PABIR family member 2 Neighboring gene PABIR family member 3 Neighboring gene ribosomal protein L13 pseudogene Neighboring gene casein kinase 1, gamma 3 pseudogene Neighboring gene embryonic testis differentiation

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

General gene information

Clone Names

  • MGC103065

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
motile sperm domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290514.1NP_001277443.1  motile sperm domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001277443.1

    Status: VALIDATED

    Source sequence(s)
    AK139795, BF467665, BG068741, BG077592, CJ046213, DV651027
    Consensus CDS
    CCDS72381.1
    UniProtKB/Swiss-Prot
    Q497P5, Q8VEL0, Q9D8Y9
    UniProtKB/TrEMBL
    Q3UT40
    Related
    ENSMUSP00000094182.3, ENSMUST00000096447.9
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  2. NM_001358456.1NP_001345385.1  motile sperm domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    BG077592, BX679674
    UniProtKB/TrEMBL
    Q3UT40
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  3. NM_027409.5NP_081685.1  motile sperm domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_081685.1

    Status: VALIDATED

    Source sequence(s)
    AK007533, BF467665, BG068741, BG077592, CJ046213, DV651027
    Consensus CDS
    CCDS30131.1
    UniProtKB/TrEMBL
    Q3UT40
    Related
    ENSMUSP00000023836.4, ENSMUST00000023836.4
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain

RNA

  1. NR_110964.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BC085100, BG077592, CJ046213

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    52433471..52459567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541541.5XP_006541604.1  motile sperm domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  2. XM_006541538.4XP_006541601.1  motile sperm domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006541601.1

    UniProtKB/TrEMBL
    Q3UT40
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  3. XM_011251017.3XP_011249319.1  motile sperm domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011249319.1

    UniProtKB/TrEMBL
    Q3UT40
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  4. XM_030251496.2XP_030107356.1  motile sperm domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  5. XM_036162092.1XP_036017985.1  motile sperm domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  6. XM_006541540.4XP_006541603.1  motile sperm domain-containing protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006541603.1

    UniProtKB/Swiss-Prot
    Q497P5, Q8VEL0, Q9D8Y9
    UniProtKB/TrEMBL
    Q3UT40
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain
  7. XM_017318617.2XP_017174106.1  motile sperm domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q497P5, Q8VEL0, Q9D8Y9
    UniProtKB/TrEMBL
    Q3UT40
    Conserved Domains (1) summary
    pfam00635
    Location:16113
    Motile_Sperm; MSP (Major sperm protein) domain

RNA

  1. XR_004940365.1 RNA Sequence