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Atp5mj ATP synthase membrane subunit j [ Mus musculus (house mouse) ]

Gene ID: 70257, updated on 5-Mar-2024

Summary

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Official Symbol
Atp5mjprovided by MGI
Official Full Name
ATP synthase membrane subunit jprovided by MGI
Primary source
MGI:MGI:1917507
See related
Ensembl:ENSMUSG00000021290 AllianceGenome:MGI:1917507
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MLQ; Mp68; Atp5mpl; 2010107E04Rik; 9430003J03Rik
Summary
Located in mitochondrion. Orthologous to human ATP5MJ (ATP synthase membrane subunit j). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 37.9), liver E18 (RPKM 32.3) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
12 F1; 12 61.14 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111927808..111933443, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111961374..111967009, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5033406O09 gene Neighboring gene predicted gene, 36757 Neighboring gene STARR-positive B cell enhancer ABC_E8504 Neighboring gene tudor domain containing 9 Neighboring gene retinal degeneration 3-like Neighboring gene predicted gene, 46381

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Hupe M, et al. Nucleic Acids Res, 2014 Jan. PMID 24165879, Free PMC Article
  2. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. McLelland GL, et al. Elife, 2018 Apr 20. PMID 29676259, Free PMC Article
  3. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial proton-transporting ATP synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
ATP synthase subunit ATP5MPL, mitochondrial
Names
6.8 kDa mitochondrial proteolipid protein
ATP synthase membrane subunit 6.8PL
ATP synthase subunit ATP5MJ, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361914.1 → NP_001348843.1  ATP synthase subunit ATP5MPL, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AC132623
    Consensus CDS
    CCDS36566.1
    UniProtKB/Swiss-Prot
    P56379
    UniProtKB/TrEMBL
    A0A1Y7VLP0
    Related
    ENSMUSP00000152618.2, ENSMUST00000222874.2
    Conserved Domains (1) summary
    pfam08039
    Location:1 → 58
    Mit_proteolip; Mitochondrial proteolipid

  2. NM_027360.3 → NP_081636.1  ATP synthase subunit ATP5MPL, mitochondrial

    See identical proteins and their annotated locations for NP_081636.1

    Status: VALIDATED

    Source sequence(s)
    AC132623, AK008333, BB618895
    Consensus CDS
    CCDS36566.1
    UniProtKB/Swiss-Prot
    P56379
    UniProtKB/TrEMBL
    A0A1Y7VLP0
    Related
    ENSMUSP00000021719.6, ENSMUST00000021719.7
    Conserved Domains (1) summary
    pfam08039
    Location:1 → 58
    Mit_proteolip; Mitochondrial proteolipid

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    111927808..111933443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P56379.1 GenPept UniProtKB/Swiss-Prot:P56379

Gene LinkOut

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