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Ctag2 cancer/testis antigen 2 [ Mus musculus (house mouse) ]

Gene ID: 70062, updated on 8-Feb-2024

Summary

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Official Symbol
Ctag2provided by MGI
Official Full Name
cancer/testis antigen 2provided by MGI
Primary source
MGI:MGI:1917312
See related
Ensembl:ENSMUSG00000031181 AllianceGenome:MGI:1917312
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700030B21Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be located in centrosome; cytoplasm; and nuclear body. Predicted to be part of EKC/KEOPS complex. Orthologous to human CTAG1A (cancer/testis antigen 1A) and CTAG2 (cancer/testis antigen 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 56.6) See more
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Genomic context

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Location:
X A7.1; X 34.64 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (64091250..64092623)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (65047644..65049017)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47271 Neighboring gene STARR-seq mESC enhancer starr_47272 Neighboring gene DDB1 and CUL4 associated factor 13 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47273 Neighboring gene STARR-seq mESC enhancer starr_47274 Neighboring gene STARR-seq mESC enhancer starr_47275 Neighboring gene STARR-seq mESC enhancer starr_47277 Neighboring gene coiled-coil domain containing 75 pseudogene Neighboring gene STARR-seq mESC enhancer starr_47278 Neighboring gene STARR-seq mESC enhancer starr_47279 Neighboring gene STARR-seq mESC enhancer starr_47280 Neighboring gene STARR-seq mESC enhancer starr_47281 Neighboring gene STARR-seq mESC enhancer starr_47282 Neighboring gene STARR-seq mESC enhancer starr_47283 Neighboring gene STARR-seq mESC enhancer starr_47284 Neighboring gene STARR-seq mESC enhancer starr_47285 Neighboring gene STARR-seq mESC enhancer starr_47286 Neighboring gene tetratricopeptide repeat domain 39C pseudogene Neighboring gene H2A histone family member L1R, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Interleukin-2-induced, melanoma-specific T cells recognize CAMEL, an unexpected translation product of LAGE-1. Aarnoudse CA, et al. Int J Cancer, 1999 Jul 30. PMID 10399963
  2. The alternative open reading frame of LAGE-1 gives rise to multiple promiscuous HLA-DR-restricted epitopes recognized by T-helper 1-type tumor-reactive CD4+ T cells. Mandic M, et al. Cancer Res, 2003 Oct 1. PMID 14559844
  3. Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes. Aradhya S, et al. Hum Mol Genet, 2001 Oct 15. PMID 11709543
  4. Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Morimoto K, et al. Sci Rep, 2020 Jun 3. PMID 32493902, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in tRNA threonylcarbamoyladenosine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of EKC/KEOPS complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cancer/testis antigen 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027302.2 → NP_081578.1  cancer/testis antigen 2

    See identical proteins and their annotated locations for NP_081578.1

    Status: VALIDATED

    Source sequence(s)
    AI503560, AK006526
    Consensus CDS
    CCDS30168.1
    UniProtKB/TrEMBL
    Q9D9S4
    Related
    ENSMUSP00000033524.3, ENSMUST00000033524.3
    Conserved Domains (1) summary
    pfam09341
    Location:131 → 202
    Pcc1; Transcription factor Pcc1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    64091250..64092623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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