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Dancr differentiation antagonizing non-protein coding RNA [ Mus musculus (house mouse) ]

Gene ID: 70036, updated on 5-Mar-2024

Summary

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Official Symbol
Dancrprovided by MGI
Official Full Name
differentiation antagonizing non-protein coding RNAprovided by MGI
Primary source
MGI:MGI:1917286
See related
Ensembl:ENSMUSG00000106943 AllianceGenome:MGI:1917286
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2700023E23Rik
Summary
Acts upstream of or within response to wounding. Is expressed in limb skin; lung; lung epithelium; and lung mesenchyme. Orthologous to human DANCR (differentiation antagonizing non-protein coding RNA). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 14.0), CNS E14 (RPKM 13.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 C3.3; 5 39.38 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (74253780..74254998)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (74093060..74094337)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 46 Neighboring gene ubiquitin specific peptidase 46, opposite strand 1 Neighboring gene predicted gene, 52817 Neighboring gene STARR-positive B cell enhancer ABC_E8062 Neighboring gene small nucleolar RNA, H/ACA box 26 Neighboring gene predicted gene, 32002 Neighboring gene RAS-like, family 11, member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. DANCR deletion retards the initiation and progression of hepatocellular carcinoma based on gene knockout and patient-derived xenograft in situ hepatoma mice model. Gan X, et al. Cancer Lett, 2022 Dec 1. PMID 36183859
  2. Exosomes Secreted by Mesenchymal Stem Cells Induce Immune Tolerance to Mouse Kidney Transplantation via Transporting LncRNA DANCR. Wu X, et al. Inflammation, 2022 Feb. PMID 34596768
  3. Effects of lncRNA DANCR on proliferation and differentiation of osteoblasts by regulating the Wnt/β-catenin pathway. Jiang SY, et al. Eur Rev Med Pharmacol Sci, 2019 Jul. PMID 31298307
  4. DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis. Yu W, et al. Oncol Rep, 2023 Feb. PMID 36601767, Free PMC Article
  5. Long non-coding RNA DANCR regulate MLL3 and thereby it determines the progression of pancreatic cancer. Liu Y, et al. J BUON, 2020 Jul-Aug. PMID 33099938

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dancr-BRG1 regulates Nfatc1 transcription and Pgc1beta-dependent metabolic shifts in osteoclastogenesis.
    Title: Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis.
  2. DANCR promotes glioma cell autophagy and proliferation via the miR33b/DLX6/ATG7 axis.
    Title: DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
  3. Exosomes Secreted by Mesenchymal Stem Cells Induce Immune Tolerance to Mouse Kidney Transplantation via Transporting LncRNA DANCR.
    Title: Exosomes Secreted by Mesenchymal Stem Cells Induce Immune Tolerance to Mouse Kidney Transplantation via Transporting LncRNA DANCR.
  4. Inhibition of the lncRNA DANCR attenuates cardiomyocyte injury induced by oxygen-glucose deprivation via the miR-19a-3p/MAPK1 axis.
    Title: Inhibition of the lncRNA DANCR attenuates cardiomyocyte injury induced by oxygen-glucose deprivation via the miR-19a-3p/MAPK1 axis.
  5. Long non-coding RNA DANCR regulate MLL3 and thereby it determines the progression of pancreatic cancer.
    Title: Long non-coding RNA DANCR regulate MLL3 and thereby it determines the progression of pancreatic cancer.
  6. Effects of lncRNA DANCR on proliferation and differentiation of osteoblasts by regulating the Wnt/beta-catenin pathway.
    Title: Effects of lncRNA DANCR on proliferation and differentiation of osteoblasts by regulating the Wnt/β-catenin pathway.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Other Names

  • hypothetical gene supported by AK045300

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015531.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC115823
    Related
    ENSMUST00000117249.3

  2. NR_145131.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC115823
    Related
    ENSMUST00000120364.3

  3. NR_145133.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC115823

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    74253780..74254998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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