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Rpp25l ribonuclease P/MRP 25 subunit-like [ Mus musculus (house mouse) ]

Gene ID: 69961, updated on 5-Mar-2024

Summary

Official Symbol
Rpp25lprovided by MGI
Official Full Name
ribonuclease P/MRP 25 subunit-likeprovided by MGI
Primary source
MGI:MGI:1917211
See related
Ensembl:ENSMUSG00000036114 AllianceGenome:MGI:1917211
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rppl25; 2810432D09Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleus. Predicted to be part of ribonuclease MRP complex. Orthologous to human RPP25L (ribonuclease P/MRP subunit p25 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 15.9), adrenal adult (RPKM 15.3) and 28 other tissues See more
Orthologs
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Genomic context

Location:
4 A5; 4 21.97 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (41712033..41713517, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (41712033..41713517, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12405 Neighboring gene ciliary neurotrophic factor receptor Neighboring gene STARR-seq mESC enhancer starr_10037 Neighboring gene STARR-positive B cell enhancer ABC_E11235 Neighboring gene dynactin 3 Neighboring gene AT-rich interaction domain 3C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in tRNA 5'-leader removal IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonuclease MRP complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ribonuclease P protein subunit p25-like protein
Names
RNase P protein subunit-like p25
alba-like protein C9orf23 homolog
rpp25-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027278.3NP_081554.2  ribonuclease P protein subunit p25-like protein

    See identical proteins and their annotated locations for NP_081554.2

    Status: VALIDATED

    Source sequence(s)
    AJ293897, BF146902
    Consensus CDS
    CCDS18068.1
    UniProtKB/Swiss-Prot
    Q99JH1, Q9CYX4
    Related
    ENSMUSP00000041477.4, ENSMUST00000038434.4
    Conserved Domains (1) summary
    pfam01918
    Location:2789
    Alba

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    41712033..41713517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)