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Mfsd11 major facilitator superfamily domain containing 11 [ Mus musculus (house mouse) ]

Gene ID: 69900, updated on 5-Mar-2024

Summary

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Official Symbol
Mfsd11provided by MGI
Official Full Name
major facilitator superfamily domain containing 11provided by MGI
Primary source
MGI:MGI:1917150
See related
Ensembl:ENSMUSG00000020818 AllianceGenome:MGI:1917150
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2600014M03Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and spinal cord. Orthologous to human MFSD11 (major facilitator superfamily domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in mammary gland adult (RPKM 25.4), testis adult (RPKM 24.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Mfsd11 in Genome Data Viewer
Location:
11 E2; 11 81.49 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (116743037..116766486)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116852211..116875660)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene matrix-remodelling associated 7 Neighboring gene STARR-seq mESC enhancer starr_31225 Neighboring gene STARR-positive B cell enhancer ABC_E7102 Neighboring gene STARR-positive B cell enhancer ABC_E4018 Neighboring gene STARR-positive B cell enhancer ABC_E2376 Neighboring gene methyltransferase like 23 Neighboring gene jumonji domain containing 6 Neighboring gene serine and arginine-rich splicing factor 2 Neighboring gene STARR-seq mESC enhancer starr_31229 Neighboring gene mannoside acetylglucosaminyltransferase 5, isoenzyme B Neighboring gene STARR-seq mESC enhancer starr_31231 Neighboring gene predicted gene, 33829 Neighboring gene STARR-seq mESC enhancer starr_31232 Neighboring gene STARR-seq mESC enhancer starr_31233 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:116898528-116898729 Neighboring gene predicted gene 11728

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene. Sureau A, et al. Nucleic Acids Res, 1997 Nov 15. PMID 9358160, Free PMC Article
  2. The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis. Perland E, et al. PLoS One, 2016. PMID 27272503, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC113819

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UNC93-like protein MFSD11
Names
major facilitator superfamily domain-containing protein 11
protein ET

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361585.1 → NP_001348514.1  UNC93-like protein MFSD11 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BC079583, BC100547
    Conserved Domains (1) summary
    cl28910
    Location:50 → 248
    MFS; Major Facilitator Superfamily

  2. NM_001361586.1 → NP_001348515.1  UNC93-like protein MFSD11 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL645542
    Conserved Domains (1) summary
    cl28910
    Location:28 → 226
    MFS; Major Facilitator Superfamily

  3. NM_001361587.1 → NP_001348516.1  UNC93-like protein MFSD11 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645542
    Conserved Domains (1) summary
    cl28910
    Location:50 → 248
    MFS; Major Facilitator Superfamily

  4. NM_178620.4 → NP_848735.1  UNC93-like protein MFSD11 isoform 1

    See identical proteins and their annotated locations for NP_848735.1

    Status: VALIDATED

    Source sequence(s)
    BC088988, BC100547
    Consensus CDS
    CCDS25681.1
    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Related
    ENSMUSP00000021173.8, ENSMUST00000021173.14
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    116743037..116766486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534144.5 → XP_006534207.1  UNC93-like protein MFSD11 isoform X1

    See identical proteins and their annotated locations for XP_006534207.1

    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  2. XM_006534142.4 → XP_006534205.1  UNC93-like protein MFSD11 isoform X1

    See identical proteins and their annotated locations for XP_006534205.1

    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  3. XM_036156971.1 → XP_036012864.1  UNC93-like protein MFSD11 isoform X1

    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Related
    ENSMUSP00000123368.3, ENSMUST00000153084.3
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  4. XM_017314745.2 → XP_017170234.1  UNC93-like protein MFSD11 isoform X1

    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  5. XM_006534143.5 → XP_006534206.1  UNC93-like protein MFSD11 isoform X1

    See identical proteins and their annotated locations for XP_006534206.1

    UniProtKB/Swiss-Prot
    A2AA30, A2AA32, B2RQK5, O54844, Q8BJ51, Q8BJ61
    Conserved Domains (1) summary
    cd17407
    Location:11 → 435
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  6. XM_036156973.1 → XP_036012866.1  UNC93-like protein MFSD11 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:50 → 248
    MFS; Major Facilitator Superfamily

  7. XM_006534146.5 → XP_006534209.1  UNC93-like protein MFSD11 isoform X3

    Conserved Domains (1) summary
    cd17407
    Location:4 → 387
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  8. XM_006534145.4 → XP_006534208.1  UNC93-like protein MFSD11 isoform X2

    Conserved Domains (1) summary
    cd17407
    Location:11 → 408
    MFS_MFSD11; UNC93-like Major facilitator superfamily domain-containing protein 11

  9. XM_036156972.1 → XP_036012865.1  UNC93-like protein MFSD11 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:50 → 248
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BJ51.1 GenPept UniProtKB/Swiss-Prot:Q8BJ51

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