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Snhg8 small nucleolar RNA host gene 8 [ Mus musculus (house mouse) ]

Gene ID: 69895, updated on 17-Mar-2024

Summary

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Official Symbol
Snhg8provided by MGI
Official Full Name
small nucleolar RNA host gene 8provided by MGI
Primary source
MGI:MGI:1917145
See related
Ensembl:ENSMUSG00000104960 AllianceGenome:MGI:1917145
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110065M07Rik; 2010109N14Rik
Summary
Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human SNHG8 (small nucleolar RNA host gene 8). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
3 G1; 3 54.58 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (123301201..123301985, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (123507552..123508336, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40143 Neighboring gene predicted gene, 35065 Neighboring gene STARR-seq mESC enhancer starr_08911 Neighboring gene serine protease 12 neurotrypsin (motopsin) Neighboring gene STARR-positive B cell enhancer ABC_E6117 Neighboring gene STARR-positive B cell enhancer mm9_chr3:123219553-123219853 Neighboring gene small nucleolar RNA, H/ACA box 24 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide pseudogene Neighboring gene STARR-seq mESC enhancer starr_08913 Neighboring gene N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 Neighboring gene STARR-seq mESC enhancer starr_08914 Neighboring gene STARR-seq mESC enhancer starr_08915

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Long noncoding RNA SNHG8 accelerates acute gouty arthritis development by upregulating AP3D1 in mice. Fang L, et al. Bioengineered, 2021 Dec. PMID 34874227, Free PMC Article
  2. Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model. Liu J, et al. Cell Death Dis, 2019 Jun 5. PMID 31165722, Free PMC Article
  3. LncRNA Snhg8 attenuates microglial inflammation response and blood-brain barrier damage in ischemic stroke through regulating miR-425-5p mediated SIRT1/NF-κB signaling. Tian J, et al. J Biochem Mol Toxicol, 2021 May. PMID 33491845
  4. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article
  5. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long non-coding RNA SNHG8 drives stress granule formation in tauopathies.
    Title: Long non-coding RNA SNHG8 drives stress granule formation in tauopathies.
  2. [LncRNA SNHG8 inhibits miR-494-3p expression to alleviate cerebral ischemia-reperfusion injury in mice].
    Title: [LncRNA SNHG8 inhibits miR-494-3p expression to alleviate cerebral ischemia-reperfusion injury in mice].
  3. Long noncoding RNA SNHG8 accelerates acute gouty arthritis development by upregulating AP3D1 in mice.
    Title: Long noncoding RNA SNHG8 accelerates acute gouty arthritis development by upregulating AP3D1 in mice.
  4. LncRNA Snhg8 attenuates microglial inflammation response and blood-brain barrier damage in ischemic stroke through regulating miR-425-5p mediated SIRT1/NF-kappaB signaling.
    Title: LncRNA Snhg8 attenuates microglial inflammation response and blood-brain barrier damage in ischemic stroke through regulating miR-425-5p mediated SIRT1/NF-κB signaling.
  5. Snhg8 overexpression combined with miR-384 knockdown led to an anti-apoptosis effect. These results reveal that the Snhg8/miR-384/Hoxa13/FAM3A axis plays a critical role in the regulation of chronic cerebral ischemia-induced neuronal apoptosis.
    Title: Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Other Names

  • small nucleolar RNA host gene (non-protein coding) 8

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028574.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124005
    Related
    ENSMUST00000198509.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    123301201..123301985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.