U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tmem147 transmembrane protein 147 [ Mus musculus (house mouse) ]

Gene ID: 69804, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Tmem147provided by MGI
Official Full Name
transmembrane protein 147provided by MGI
Primary source
MGI:MGI:1915011
See related
Ensembl:ENSMUSG00000006315 AllianceGenome:MGI:1915011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nifie14; 2010004E11Rik; 5033425B17Rik
Summary
Predicted to enable ribosome binding activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of protein-containing complex. Is expressed in genitourinary system. Orthologous to human TMEM147 (transmembrane protein 147). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 145.9), adrenal adult (RPKM 135.5) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7 B1; 7 19.23 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30427126..30428959, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30727701..30729534, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2200002J24 gene Neighboring gene STARR-positive B cell enhancer ABC_E9108 Neighboring gene ATPase, H+/K+ exchanging, gastric, alpha polypeptide Neighboring gene STARR-positive B cell enhancer ABC_E11349 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Neighboring gene suprabasin Neighboring gene dermokine

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Georgas KM, et al. Dev Dyn, 2011 Jun. PMID 21491542, Free PMC Article
  2. Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Combes AN, et al. Dev Dyn, 2009 May. PMID 19334288, Free PMC Article
  3. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC6895

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in multi-pass transmembrane protein insertion into ER membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to nuclear inner membrane ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of multi-pass translocon complex ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
BOS complex subunit TMEM147
Names
seven transmembrane domain protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027215.2 → NP_081491.2  BOS complex subunit TMEM147

    See identical proteins and their annotated locations for NP_081491.2

    Status: VALIDATED

    Source sequence(s)
    AK010168, AK160267
    Consensus CDS
    CCDS39890.1
    UniProtKB/Swiss-Prot
    Q8CI89, Q9CQG6, Q9D8F0
    UniProtKB/TrEMBL
    A0A140LJ56, B2RVQ1
    Related
    ENSMUSP00000006478.9, ENSMUST00000006478.10
    Conserved Domains (1) summary
    pfam09767
    Location:2 → 158
    DUF2053; Predicted membrane protein (DUF2053)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    30427126..30428959 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153426.1 → XP_036009319.1  BOS complex subunit TMEM147 isoform X1

    UniProtKB/TrEMBL
    A0A140LIQ8
    Related
    ENSMUSP00000146918.2, ENSMUST00000209065.2
    Conserved Domains (1) summary
    pfam09767
    Location:1 → 106
    DUF2053; Predicted membrane protein (DUF2053)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQG6.1 GenPept UniProtKB/Swiss-Prot:Q9CQG6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous