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Bod1 biorientation of chromosomes in cell division 1 [ Mus musculus (house mouse) ]

Gene ID: 69556, updated on 5-Mar-2024

Summary

Official Symbol
Bod1provided by MGI
Official Full Name
biorientation of chromosomes in cell division 1provided by MGI
Primary source
MGI:MGI:1916806
See related
Ensembl:ENSMUSG00000044502 AllianceGenome:MGI:1916806
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bodq1; BOD2.1; Fam44b; 2310022M17Rik
Summary
Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphoprotein phosphatase activity. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm; cytoskeleton; and kinetochore. Predicted to be part of outer kinetochore. Predicted to be active in centrosome; spindle microtubule; and spindle pole. Orthologous to several human genes including BOD1 (biorientation of chromosomes in cell division 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 56.8), whole brain E14.5 (RPKM 56.0) and 28 other tissues See more
Orthologs
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Genomic context

Location:
11 A4; 11 18.55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (31615150..31621862, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (31665150..31671862, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35012 Neighboring gene predicted gene, 39672 Neighboring gene STARR-seq mESC enhancer starr_29080 Neighboring gene predicted gene, 35063 Neighboring gene STARR-positive B cell enhancer ABC_E137 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:31571987-31572170 Neighboring gene predicted gene, 53678 Neighboring gene predicted gene, 39673

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC144642

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein phosphatase 2A binding ISO
Inferred from Sequence Orthology
more info
 
enables protein phosphatase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Set1C/COMPASS complex ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 
part_of outer kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
biorientation of chromosomes in cell division protein 1
Names
biorientation defective protein 1
bone length and organs 1
bone length and organs QTL 1
family with sequence similarity 44, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024919.1NP_001020090.1  biorientation of chromosomes in cell division protein 1

    See identical proteins and their annotated locations for NP_001020090.1

    Status: PROVISIONAL

    Source sequence(s)
    AK009485, BB616782, BF022873
    Consensus CDS
    CCDS24513.1
    UniProtKB/Swiss-Prot
    Q5SQY2
    UniProtKB/TrEMBL
    Q08EE0
    Related
    ENSMUSP00000056417.8, ENSMUST00000058060.14
    Conserved Domains (1) summary
    pfam05205
    Location:43136
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    31615150..31621862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)