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Tmco2 transmembrane and coiled-coil domains 2 [ Mus musculus (house mouse) ]

Gene ID: 69469, updated on 5-Mar-2024

Summary

Official Symbol
Tmco2provided by MGI
Official Full Name
transmembrane and coiled-coil domains 2provided by MGI
Primary source
MGI:MGI:1916719
See related
Ensembl:ENSMUSG00000078577 AllianceGenome:MGI:1916719
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700028F16Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMCO2 (transmembrane and coiled-coil domains 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 175.1) See more
Orthologs
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Genomic context

Location:
4 D2.2; 4 56.8 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (120962848..120966414, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (121105651..121109217, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11259 Neighboring gene collagen, type IX, alpha 2 Neighboring gene zinc metallopeptidase, STE24 Neighboring gene predicted gene, 23540 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:120770755-120770962 Neighboring gene predicted gene 12882 Neighboring gene SEC61 translocon subunit gamma, pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane and coiled-coil domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081312.2NP_001074781.1  transmembrane and coiled-coil domain-containing protein 2

    See identical proteins and their annotated locations for NP_001074781.1

    Status: VALIDATED

    Source sequence(s)
    AL669949
    Consensus CDS
    CCDS38866.1
    UniProtKB/Swiss-Prot
    P0C1V4
    UniProtKB/TrEMBL
    J3JS82
    Related
    ENSMUSP00000101875.4, ENSMUST00000106268.4
    Conserved Domains (1) summary
    pfam15844
    Location:11182
    TMCCDC2; Transmembrane and coiled-coil domain-containing protein 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    120962848..120966414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)