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Zc3h15 zinc finger CCCH-type containing 15 [ Mus musculus (house mouse) ]

Gene ID: 69082, updated on 5-Mar-2024

Summary

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Official Symbol
Zc3h15provided by MGI
Official Full Name
zinc finger CCCH-type containing 15provided by MGI
Primary source
MGI:MGI:1919747
See related
Ensembl:ENSMUSG00000027091 AllianceGenome:MGI:1919747
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FM22; Ierepo4; 1700006A17Rik; 1810012H02Rik; 2610312B22Rik
Summary
Predicted to enable metal ion binding activity. Acts upstream of or within cytokine-mediated signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZC3H15 (zinc finger CCCH-type containing 15). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 53.2), CNS E18 (RPKM 33.0) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 D; 2 49.33 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (83474922..83494961)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (83644578..83664617)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_04981 Neighboring gene fructose-bisphosphate aldolase A pseudogene Neighboring gene STARR-seq mESC enhancer starr_04983 Neighboring gene family with sequence similarity 54, member A pseudogene Neighboring gene STARR-seq mESC enhancer starr_04984 Neighboring gene STARR-seq mESC enhancer starr_04985 Neighboring gene STARR-positive B cell enhancer ABC_E11141 Neighboring gene STARR-positive B cell enhancer ABC_E11142 Neighboring gene STARR-positive B cell enhancer ABC_E7831 Neighboring gene STARR-positive B cell enhancer mm9_chr2:83505584-83505885 Neighboring gene STARR-seq mESC enhancer starr_04989 Neighboring gene DNA methyltransferase 3-like, pseudogene 1 Neighboring gene STARR-positive B cell enhancer ABC_E2039 Neighboring gene STARR-positive B cell enhancer ABC_E7832 Neighboring gene integrin alpha V Neighboring gene family with sequence similarity 171, member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Subtraction cloning and initial characterization of novel epo-immediate response genes. Gregory RC, et al. Cytokine, 2000 Jul. PMID 10880228
  2. Identification of DRG family regulatory proteins (DFRPs): specific regulation of DRG1 and DRG2. Ishikawa K, et al. Genes Cells, 2005 Feb. PMID 15676025
  3. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
  4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cytokine-mediated signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger CCCH domain-containing protein 15
Names
DRG family-regulatory protein 1
epo-immediate response gene protein FM22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026934.3 → NP_081210.2  zinc finger CCCH domain-containing protein 15

    See identical proteins and their annotated locations for NP_081210.2

    Status: PROVISIONAL

    Source sequence(s)
    AL772301, BX294652
    Consensus CDS
    CCDS16180.1
    UniProtKB/Swiss-Prot
    Q3TIV5, Q3TWQ0, Q3U855, Q8K2B6, Q8K346, Q9CVM4, Q9DAP2
    Related
    ENSMUSP00000080301.7, ENSMUST00000081591.7
    Conserved Domains (1) summary
    cl25637
    Location:1 → 325
    DFRP_C; DRG Family Regulatory Proteins, Tma46

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    83474922..83494961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_027023.1: Suppressed sequence

    Description
    NM_027023.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TIV5.2 GenPept UniProtKB/Swiss-Prot:Q3TIV5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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