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Nol11 nucleolar protein 11 [ Mus musculus (house mouse) ]

Gene ID: 68979, updated on 5-Mar-2024

Summary

Official Symbol
Nol11provided by MGI
Official Full Name
nucleolar protein 11provided by MGI
Primary source
MGI:MGI:1916229
See related
Ensembl:ENSMUSG00000018433 AllianceGenome:MGI:1916229
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500002M01Rik
Summary
Predicted to be involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of t-UTP complex. Predicted to be active in nucleolus. Orthologous to human NOL11 (nucleolar protein 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 10.3), whole brain E14.5 (RPKM 8.4) and 27 other tissues See more
Orthologs
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Genomic context

Location:
11 E1; 11 70.19 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (107057477..107080207, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (107166651..107189381, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810010H24 gene Neighboring gene STARR-positive B cell enhancer ABC_E9377 Neighboring gene STARR-positive B cell enhancer mm9_chr11:106905708-106906009 Neighboring gene bromodomain PHD finger transcription factor Neighboring gene STARR-positive B cell enhancer ABC_E2373 Neighboring gene STARR-positive B cell enhancer ABC_E5290 Neighboring gene STARR-positive B cell enhancer ABC_E10725 Neighboring gene STARR-seq mESC enhancer starr_30956 Neighboring gene STARR-positive B cell enhancer ABC_E10726 Neighboring gene STARR-seq mESC enhancer starr_30959 Neighboring gene STARR-seq mESC enhancer starr_30962 Neighboring gene predicted gene 11715 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:107050502-107050685 Neighboring gene STARR-seq mESC enhancer starr_30965 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 39425 Neighboring gene actin, gamma, cytoplasmic 1 pseudogene Neighboring gene phosphatidylinositol transfer protein, cytoplasmic 1 Neighboring gene STARR-positive B cell enhancer ABC_E7084 Neighboring gene STARR-seq mESC enhancer starr_30969 Neighboring gene STARR-positive B cell enhancer mm9_chr11:107194258-107194558 Neighboring gene predicted gene 11716

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in maturation of SSU-rRNA ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of t-UTP complex ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161329.2NP_001154801.1  nucleolar protein 11 isoform 2

    See identical proteins and their annotated locations for NP_001154801.1

    Status: VALIDATED

    Source sequence(s)
    AK076704, AK078524, AL596116
    Consensus CDS
    CCDS48965.1
    UniProtKB/Swiss-Prot
    Q8BJW5
    Related
    ENSMUSP00000102368.2, ENSMUST00000106757.8
    Conserved Domains (1) summary
    pfam08168
    Location:200243
    NUC205; NUC205 domain
  2. NM_001363078.1NP_001350007.1  nucleolar protein 11 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL596116
    Conserved Domains (1) summary
    pfam08168
    Location:131174
    NUC205; NUC205 domain
  3. NM_133702.3NP_598463.2  nucleolar protein 11 isoform 1

    See identical proteins and their annotated locations for NP_598463.2

    Status: VALIDATED

    Source sequence(s)
    AK076704, AK078524, AL596116
    Consensus CDS
    CCDS25566.1
    UniProtKB/Swiss-Prot
    Q8BGJ1, Q8BJW5, Q8R3Q3, Q99KA5
    Related
    ENSMUSP00000018577.8, ENSMUST00000018577.8
    Conserved Domains (1) summary
    pfam08168
    Location:200243
    NUC205; NUC205 domain

RNA

  1. NR_156439.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL596116

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    107057477..107080207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)