Cdan1 codanin 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cdan1provided by MGI
Official Full Name: codanin 1provided by MGI
Primary source: MGI:MGI:1916218
See related: Ensembl:ENSMUSG00000027284 AllianceGenome:MGI:1916218
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: CDA1; CDAI; CDA-I; codanin-1; 1500015A01Rik
Summary: Predicted to be involved in chromatin assembly and negative regulation of DNA replication. Predicted to act upstream of or within protein localization. Located in endomembrane system and nucleus. Is expressed in several structures, including adipose tissue; central nervous system; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia and congenital dyserythropoietic anemia type Ia. Orthologous to human CDAN1 (codanin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in thymus adult (RPKM 17.2), testis adult (RPKM 7.4) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 E5; 2 60.37 cM

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (120546635..120561998, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (120716154..120731517, complement)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (4) 1 citation
Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI448026 (e-PCR)
- UniSTS:159008

AW492297 (e-PCR)
- UniSTS:178687

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in chromatin organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chromatin organization	ISO Inferred from Sequence Orthology more info
involved_in import into nucleus	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within nuclear envelope organization	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within protein localization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in endomembrane system	IDA Inferred from Direct Assay more info	PubMed
located_in endomembrane system	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: codanin-1

Names: congenital dyserythropoietic anemia type I; congenital dyserythropoietic anemia, type I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.