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Smim11 small integral membrane protein 11 [ Mus musculus (house mouse) ]

Gene ID: 68936, updated on 5-Mar-2024

Summary

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Official Symbol
Smim11provided by MGI
Official Full Name
small integral membrane protein 11provided by MGI
Primary source
MGI:MGI:1916186
See related
Ensembl:ENSMUSG00000051989 AllianceGenome:MGI:1916186
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam165b; Smim11a; C21orf51; 1190017O12Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human SMIM11 (small integral membrane protein 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 21.5), CNS E11.5 (RPKM 20.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 C4; 16 53.55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (92098131..92109929)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (92301241..92313041)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41497 Neighboring gene STARR-seq mESC enhancer starr_41508 Neighboring gene potassium voltage-gated channel, Isk-related subfamily, gene 2 Neighboring gene STARR-positive B cell enhancer ABC_E3175 Neighboring gene RIKEN cDNA 1700048M11 gene Neighboring gene family with sequence similarity 243 Neighboring gene small integral membrane protein 34

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic imbalances in preleukemic thymuses. Verlaet M, et al. Biochem Biophys Res Commun, 2001 Apr 27. PMID 11322760
  2. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Reymond A, et al. Genomics, 2001 Nov. PMID 11707072
  3. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, et al. Nature, 2002 Dec 5. PMID 12466855
  4. Human chromosome 21 gene expression atlas in the mouse. Reymond A, et al. Nature, 2002 Dec 5. PMID 12466854
  5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small integral membrane protein 11
Names
family with sequence similarity 165, member B
protein FAM165B
small integral membrane protein 11A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138743.2 → NP_620082.1  small integral membrane protein 11

    See identical proteins and their annotated locations for NP_620082.1

    Status: VALIDATED

    Source sequence(s)
    AK004538, BM932344
    Consensus CDS
    CCDS37404.1
    UniProtKB/Swiss-Prot
    Q99J19
    Related
    ENSMUSP00000070724.5, ENSMUST00000063641.11
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 50
    FAM165; FAM165 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    92098131..92109929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249260.2 → XP_030105120.1  small integral membrane protein 11 isoform X1

    UniProtKB/Swiss-Prot
    Q99J19
    Conserved Domains (1) summary
    pfam14981
    Location:4 → 50
    FAM165; FAM165 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99J19.1 GenPept UniProtKB/Swiss-Prot:Q99J19

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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