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Tmem140 transmembrane protein 140 [ Mus musculus (house mouse) ]

Gene ID: 68487, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem140provided by MGI
Official Full Name
transmembrane protein 140provided by MGI
Primary source
MGI:MGI:1915737
See related
Ensembl:ENSMUSG00000057137 AllianceGenome:MGI:1915737
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110007F12Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMEM140 (transmembrane protein 140). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 26.9), subcutaneous fat pad adult (RPKM 16.7) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 B1; 6 15.18 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (34840081..34851881)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (34863146..34874946)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ATP/GTP binding protein-like 3 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene predicted gene, 46957 Neighboring gene cell cycle regulator of NHEJ Neighboring gene WD repeat domain 91 Neighboring gene STARR-positive B cell enhancer mm9_chr6:34860831-34861132 Neighboring gene stimulated by retinoic acid gene 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 140

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368365.1 → NP_001355294.1  transmembrane protein 140

    Status: VALIDATED

    Source sequence(s)
    AC153869
    Consensus CDS
    CCDS19996.1
    UniProtKB/Swiss-Prot
    Q8BGY5, Q8VDY2
    Conserved Domains (1) summary
    pfam14985
    Location:6 → 185
    TM140; TM140 protein family

  2. NM_197986.3 → NP_932103.1  transmembrane protein 140

    See identical proteins and their annotated locations for NP_932103.1

    Status: VALIDATED

    Source sequence(s)
    AC153869
    Consensus CDS
    CCDS19996.1
    UniProtKB/Swiss-Prot
    Q8BGY5, Q8VDY2
    Related
    ENSMUSP00000074482.4, ENSMUST00000074949.4
    Conserved Domains (1) summary
    pfam14985
    Location:6 → 185
    TM140; TM140 protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    34840081..34851881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506541.3 → XP_006506604.1  transmembrane protein 140 isoform X1

    See identical proteins and their annotated locations for XP_006506604.1

    UniProtKB/Swiss-Prot
    Q8BGY5, Q8VDY2
    Conserved Domains (1) summary
    pfam14985
    Location:6 → 185
    TM140; TM140 protein family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BGY5.1 GenPept UniProtKB/Swiss-Prot:Q8BGY5

Gene LinkOut

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