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Ccdc163 coiled-coil domain containing 163 [ Mus musculus (house mouse) ]

Gene ID: 68394, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc163provided by MGI
Official Full Name
coiled-coil domain containing 163provided by MGI
Primary source
MGI:MGI:1915644
See related
Ensembl:ENSMUSG00000028689 AllianceGenome:MGI:1915644
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
0610037D15Rik; 4933430J04Rik
Summary
Is expressed in central nervous system and retina. Orthologous to human CCDC163 (coiled-coil domain containing 163). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 19.0), bladder adult (RPKM 4.9) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc163 in Genome Data Viewer
Location:
4 D1; 4 53.29 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116565537..116572881)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116708340..116715684)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 25137 Neighboring gene expressed sequence AV051173 Neighboring gene peroxiredoxin 1 Neighboring gene STARR-positive B cell enhancer ABC_E9593 Neighboring gene STARR-positive B cell enhancer ABC_E2706 Neighboring gene methylmalonic aciduria cblC type, with homocystinuria Neighboring gene STARR-positive B cell enhancer ABC_E37 Neighboring gene STARR-seq mESC enhancer starr_11147 Neighboring gene testis-specific kinase 2 Neighboring gene STARR-seq mESC enhancer starr_11148 Neighboring gene STARR-seq mESC enhancer starr_11149 Neighboring gene STARR-positive B cell enhancers ABC_E11715 and ABC_E10249 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116480418-116480527 Neighboring gene target of EGR1, member 1 (nuclear) Neighboring gene mutY DNA glycosylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Diversification of stem cell molecular repertoire by alternative splicing. Pritsker M, et al. Proc Natl Acad Sci U S A, 2005 Oct 4. PMID 16183747, Free PMC Article
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
transmembrane protein CCDC163

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356315.1 → NP_001343244.1  transmembrane protein CCDC163 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL683847, BE950263, BY248144, CD741104
    Conserved Domains (2) summary
    TIGR02169
    Location:158 → 303
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    TIGR04211
    Location:98 → 179
    SH3_and_anchor; SH3 domain protein

  2. NM_026714.3 → NP_080990.2  transmembrane protein CCDC163 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL683847, BE950263, BY248144, CD741104
    Consensus CDS
    CCDS38853.1
    UniProtKB/TrEMBL
    A2AGD7
    Related
    ENSMUSP00000102072.3, ENSMUST00000106464.3
    Conserved Domains (1) summary
    TIGR02169
    Location:145 → 290
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

RNA

  1. NR_151451.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL683847, BC022718, BE950263, BY248144

  2. NR_151452.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL683847, BC022733, BE950263, BY248144

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116565537..116572881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253737.1 → XP_030109597.1  transmembrane protein CCDC163 isoform X10

    UniProtKB/TrEMBL
    A8Y5M9
    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 173
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  2. XM_006503369.4 → XP_006503432.1  transmembrane protein CCDC163 isoform X12

  3. XM_017320378.3 → XP_017175867.1  transmembrane protein CCDC163 isoform X14

  4. XM_006503358.5 → XP_006503421.1  transmembrane protein CCDC163 isoform X1

    See identical proteins and their annotated locations for XP_006503421.1

    Conserved Domains (2) summary
    TIGR02168
    Location:81 → 254
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:158 → 242
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  5. XM_006503363.5 → XP_006503426.1  transmembrane protein CCDC163 isoform X6

    Conserved Domains (1) summary
    TIGR04211
    Location:78 → 179
    SH3_and_anchor; SH3 domain protein

  6. XM_017320376.3 → XP_017175865.1  transmembrane protein CCDC163 isoform X7

    Conserved Domains (1) summary
    TIGR04211
    Location:78 → 179
    SH3_and_anchor; SH3 domain protein

  7. XM_006503368.4 → XP_006503431.1  transmembrane protein CCDC163 isoform X11

    UniProtKB/TrEMBL
    A2AGD6
    Conserved Domains (1) summary
    TIGR04211
    Location:78 → 179
    SH3_and_anchor; SH3 domain protein

  8. XM_006503360.5 → XP_006503423.1  transmembrane protein CCDC163 isoform X3

    Conserved Domains (1) summary
    TIGR02169
    Location:145 → 229
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  9. XM_030253740.2 → XP_030109600.1  transmembrane protein CCDC163 isoform X13

    UniProtKB/TrEMBL
    A2AGD6
    Related
    ENSMUSP00000120572.2, ENSMUST00000130828.8
    Conserved Domains (1) summary
    TIGR04211
    Location:85 → 166
    SH3_and_anchor; SH3 domain protein

  10. XM_030253736.2 → XP_030109596.1  transmembrane protein CCDC163 isoform X9

    UniProtKB/TrEMBL
    A2AGD6
    Conserved Domains (1) summary
    TIGR04211
    Location:65 → 166
    SH3_and_anchor; SH3 domain protein

  11. XM_006503359.4 → XP_006503422.1  transmembrane protein CCDC163 isoform X2

    Conserved Domains (2) summary
    TIGR02168
    Location:80 → 253
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:157 → 241
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  12. XM_006503361.4 → XP_006503424.1  transmembrane protein CCDC163 isoform X4

    Conserved Domains (2) summary
    TIGR02168
    Location:67 → 240
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:144 → 228
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  13. XM_036164389.1 → XP_036020282.1  transmembrane protein CCDC163 isoform X5

  14. XM_036164391.1 → XP_036020284.1  transmembrane protein CCDC163 isoform X10

    UniProtKB/TrEMBL
    A8Y5M9
    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 173
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  15. XM_017320377.3 → XP_017175866.1  transmembrane protein CCDC163 isoform X8

    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 112
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  16. XM_006503365.4 → XP_006503428.1  transmembrane protein CCDC163 isoform X8

    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 112
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  17. XM_030253738.2 → XP_030109598.1  transmembrane protein CCDC163 isoform X10

    UniProtKB/TrEMBL
    A8Y5M9
    Related
    ENSMUSP00000102070.3, ENSMUST00000106462.9
    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 173
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  18. XM_036164390.1 → XP_036020283.1  transmembrane protein CCDC163 isoform X8

    Conserved Domains (1) summary
    TIGR02169
    Location:28 → 112
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

RNA

  1. XR_003955004.2 RNA Sequence

  2. XR_376350.4 RNA Sequence

  3. XR_001784191.3 RNA Sequence

  4. XR_003955003.2 RNA Sequence

  5. XR_003955001.2 RNA Sequence

    Related
    ENSMUST00000030452.13

  6. XR_004941952.1 RNA Sequence

  7. XR_001784194.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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