Aspdh aspartate dehydrogenase domain containing [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Aspdhprovided by MGI
Official Full Name: aspartate dehydrogenase domain containingprovided by MGI
Primary source: MGI:MGI:1915602
See related: Ensembl:ENSMUSG00000038704 AllianceGenome:MGI:1915602
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 0610012D14Rik
Summary: Predicted to enable NADP binding activity and aspartate dehydrogenase activity. Predicted to be involved in NAD biosynthetic process. Predicted to act upstream of or within pyridine nucleotide biosynthetic process. Orthologous to human ASPDH (aspartate dehydrogenase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver adult (RPKM 186.3), kidney adult (RPKM 84.0) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 7 B3; 7 28.83 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (44114859..44117175)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (44465435..44467751)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables NADP binding	IEA Inferred from Electronic Annotation more info
enables aspartate dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NAD biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: aspartate dehydrogenase domain-containing protein

Names: putative L-aspartate dehydrogenase

NP_080966.1

EC 1.4.1.21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026690.1 → NP_080966.1 aspartate dehydrogenase domain-containing protein

See identical proteins and their annotated locations for NP_080966.1

Status: PROVISIONAL

Source sequence(s)

AK002587

Consensus CDS

CCDS21207.1

UniProtKB/Swiss-Prot

Q8VCQ0, Q9DCQ2

UniProtKB/TrEMBL

D3Z253

Related

ENSMUSP00000039202.5, ENSMUST00000035929.11

Conserved Domains (2) summary

pfam01958
Location:176 → 265

DUF108; Domain of unknown function DUF108

pfam03447
Location:17 → 127

NAD_binding_3; Homoserine dehydrogenase, NAD binding domain