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Fam133b family with sequence similarity 133, member B [ Mus musculus (house mouse) ]

Gene ID: 68152, updated on 5-Mar-2024

Summary

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Official Symbol
Fam133bprovided by MGI
Official Full Name
family with sequence similarity 133, member Bprovided by MGI
Primary source
MGI:MGI:1915402
See related
Ensembl:ENSMUSG00000058503 AllianceGenome:MGI:1915402
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2900022K02Rik; 5830415L20Rik
Summary
Is expressed in cerebral cortex ventricular layer. Orthologous to several human genes including FAM133B (family with sequence similarity 133 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 10.0), CNS E14 (RPKM 7.3) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 A1; 5 2.22 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (3593833..3620548)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (3543833..3570548)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12301 Neighboring gene STARR-seq mESC enhancer starr_12302 Neighboring gene predicted gene, 36548 Neighboring gene STARR-seq mESC enhancer starr_12303 Neighboring gene STARR-seq mESC enhancer starr_12305 Neighboring gene cyclin dependent kinase 6, opposite strand transcript 1 Neighboring gene STARR-seq mESC enhancer starr_12306 Neighboring gene STARR-seq mESC enhancer starr_12307 Neighboring gene STARR-positive B cell enhancer ABC_E10299 Neighboring gene STARR-positive B cell enhancer ABC_E2150 Neighboring gene cyclin dependent kinase 6 Neighboring gene STARR-positive B cell enhancer ABC_E2736 Neighboring gene STARR-seq mESC enhancer starr_12309 Neighboring gene predicted gene, 29868 Neighboring gene STARR-seq mESC enhancer starr_12311 Neighboring gene STARR-positive B cell enhancer ABC_E4741 Neighboring gene RIKEN cDNA 1700109H08 gene Neighboring gene STARR-seq mESC enhancer starr_12313 Neighboring gene STARR-seq mESC enhancer starr_12314 Neighboring gene STARR-positive B cell enhancer ABC_E429 Neighboring gene RNA binding motif protein 48 Neighboring gene peroxisomal biogenesis factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
  2. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM133B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042501.1 → NP_001035966.1  protein FAM133B

    See identical proteins and their annotated locations for NP_001035966.1

    Status: VALIDATED

    Source sequence(s)
    AC090443, AK008115, BY711248, CK791263
    Consensus CDS
    CCDS39000.1
    UniProtKB/Swiss-Prot
    B2RVR0, Q78HY5, Q9CVI2
    Related
    ENSMUSP00000111189.4, ENSMUST00000115527.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    3593833..3620548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_026583.2: Suppressed sequence

    Description
    NM_026583.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CVI2.3 GenPept UniProtKB/Swiss-Prot:Q9CVI2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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