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Dcakd dephospho-CoA kinase domain containing [ Mus musculus (house mouse) ]

Gene ID: 68087, updated on 11-Apr-2024

Summary

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Official Symbol
Dcakdprovided by MGI
Official Full Name
dephospho-CoA kinase domain containingprovided by MGI
Primary source
MGI:MGI:1915337
See related
Ensembl:ENSMUSG00000020935 AllianceGenome:MGI:1915337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3010024O21Rik; 6720485C15Rik
Summary
Predicted to enable dephospho-CoA kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Located in mitochondrion. Is expressed in testis. Orthologous to human DCAKD (dephospho-CoA kinase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 63.5), whole brain E14.5 (RPKM 59.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 E1; 11 66.71 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (102884873..102919107, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (102994047..103028370, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene complement component 1, q subcomponent-like 1 Neighboring gene RIKEN cDNA 2410004I01 gene Neighboring gene predicted gene, 34620 Neighboring gene STARR-seq mESC enhancer starr_30823 Neighboring gene microRNA 6931 Neighboring gene STARR-positive B cell enhancer ABC_E8458 Neighboring gene STARR-positive B cell enhancer ABC_E7071 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:102889625-102889808 Neighboring gene STARR-seq mESC enhancer starr_30825 Neighboring gene N-myristoyltransferase 1 Neighboring gene predicted gene, 42090 Neighboring gene phospholipase C, delta 3 Neighboring gene STARR-seq mESC enhancer starr_30831

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
  2. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  3. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  4. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  5. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ22955

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables dephospho-CoA kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dephospho-CoA kinase activity ISO
Inferred from Sequence Orthology
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in coenzyme A biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
dephospho-CoA kinase domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417999.1 → NP_001404928.1  dephospho-CoA kinase domain-containing protein

    Status: VALIDATED

    Source sequence(s)
    AL731670, AL731805
    UniProtKB/Swiss-Prot
    Q8BHC4

  2. NM_026551.4 → NP_080827.2  dephospho-CoA kinase domain-containing protein

    See identical proteins and their annotated locations for NP_080827.2

    Status: VALIDATED

    Source sequence(s)
    AL731670
    Consensus CDS
    CCDS25510.1
    UniProtKB/Swiss-Prot
    Q8BHC4
    Related
    ENSMUSP00000021313.3, ENSMUST00000021313.9
    Conserved Domains (1) summary
    PRK00081
    Location:1 → 196
    coaE; dephospho-CoA kinase; Reviewed

RNA

  1. NR_184666.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL731670, AL731805

  2. NR_184667.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL731670, AL731805

  3. NR_184668.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL731670, AL731805

  4. NR_184669.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL731670, AL731805

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    102884873..102919107 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BHC4.1 GenPept UniProtKB/Swiss-Prot:Q8BHC4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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