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Gpn3 GPN-loop GTPase 3 [ Mus musculus (house mouse) ]

Gene ID: 68080, updated on 5-Mar-2024

Summary

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Official Symbol
Gpn3provided by MGI
Official Full Name
GPN-loop GTPase 3provided by MGI
Primary source
MGI:MGI:1289326
See related
Ensembl:ENSMUSG00000029464 AllianceGenome:MGI:1289326
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atpbd1c; D5Ertd708e; A930018B01Rik
Summary
Predicted to enable GTPase activity. Predicted to be part of protein-containing complex. Orthologous to human GPN3 (GPN-loop GTPase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 23.5), liver E14.5 (RPKM 21.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 F; 5 62.33 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (122510571..122520834)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (122372508..122382771)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene PTC7 protein phosphatase homolog Neighboring gene RAD9 checkpoint clamp component B Neighboring gene STARR-positive B cell enhancer ABC_E2761 Neighboring gene VPS29 retromer complex component Neighboring gene STARR-seq mESC enhancer starr_14283 Neighboring gene family with sequence similarity 216, member A Neighboring gene predicted gene, 32853 Neighboring gene STARR-positive B cell enhancer ABC_E4787 Neighboring gene STARR-positive B cell enhancer ABC_E8077 Neighboring gene actin related protein 2/3 complex, subunit 3 Neighboring gene anaphase promoting complex subunit 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
GPN-loop GTPase 3
Names
ATP-binding domain 1 family member C
protein x 0004

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024216.2 → NP_077178.1  GPN-loop GTPase 3

    See identical proteins and their annotated locations for NP_077178.1

    Status: VALIDATED

    Source sequence(s)
    AC113285
    Consensus CDS
    CCDS19647.1
    UniProtKB/Swiss-Prot
    Q8BU32, Q9D3W4
    Related
    ENSMUSP00000031420.5, ENSMUST00000031420.11
    Conserved Domains (2) summary
    COG1100
    Location:1 → 219
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:8 → 254
    ATP_bind_1; Conserved hypothetical ATP binding protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    122510571..122520834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D3W4.1 GenPept UniProtKB/Swiss-Prot:Q9D3W4

Gene LinkOut

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