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Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [ Mus musculus (house mouse) ]

Gene ID: 67973, updated on 5-Mar-2024

Summary

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Official Symbol
Mphosph10provided by MGI
Official Full Name
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)provided by MGI
Primary source
MGI:MGI:1915223
See related
Ensembl:ENSMUSG00000030521 AllianceGenome:MGI:1915223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810453H10Rik; 5730405D16Rik
Summary
Predicted to act upstream of or within rRNA processing. Predicted to be located in chromosome and nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is expressed in esophagus; lung; pituitary gland; urethra; and vertebral axis musculature. Orthologous to human MPHOSPH10 (M-phase phosphoprotein 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 16.9), liver E14 (RPKM 10.4) and 11 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 34.64 cM; 7 C
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64026289..64041984, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64376541..64392236, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19037 Neighboring gene myotubularin related protein 10 Neighboring gene STARR-seq mESC enhancer starr_19038 Neighboring gene STARR-seq mESC enhancer starr_19039 Neighboring gene SET translocation pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:71537088-71537271 Neighboring gene STARR-positive B cell enhancer ABC_E4931 Neighboring gene FANCD2/FANCI-associated nuclease 1 Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene STARR-seq mESC enhancer starr_19041 Neighboring gene STARR-seq mESC enhancer starr_19042

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes. Stefan M, et al. BMC Genomics, 2005 Nov 9. PMID 16280085, Free PMC Article
  2. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362, Free PMC Article
  3. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mpp10 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mpp10 complex ISO
Inferred from Sequence Orthology
more info
  
located_in chromosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
part_of sno(s)RNA-containing ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
U3 small nucleolar ribonucleoprotein protein MPP10
Names
m phase phosphoprotein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026483.2 → NP_080759.2  U3 small nucleolar ribonucleoprotein protein MPP10

    See identical proteins and their annotated locations for NP_080759.2

    Status: VALIDATED

    Source sequence(s)
    AK008785, AK017490, AV222458, CK390971
    Consensus CDS
    CCDS21333.1
    UniProtKB/Swiss-Prot
    E9QM78, Q810V0
    UniProtKB/TrEMBL
    A0PJ89
    Related
    ENSMUSP00000032735.6, ENSMUST00000032735.8
    Conserved Domains (1) summary
    pfam04006
    Location:22 → 632
    Mpp10; Mpp10 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    64026289..64041984 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q810V0.2 GenPept UniProtKB/Swiss-Prot:Q810V0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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