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Mtres1 mitochondrial transcription rescue factor 1 [ Mus musculus (house mouse) ]

Gene ID: 67851, updated on 5-Mar-2024

Summary

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Official Symbol
Mtres1provided by MGI
Official Full Name
mitochondrial transcription rescue factor 1provided by MGI
Primary source
MGI:MGI:1915101
See related
Ensembl:ENSMUSG00000019797 AllianceGenome:MGI:1915101
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700021F05Rik
Summary
Predicted to enable ribosomal large subunit binding activity and tRNA binding activity. Predicted to be involved in regulation of mitochondrial transcription and rescue of stalled ribosome. Located in mitochondrion. Orthologous to human MTRES1 (mitochondrial transcription rescue factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 3.3), CNS E11.5 (RPKM 3.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B2; 10 23.01 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (43401115..43417037, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (43525119..43541041, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47889 Neighboring gene presequence translocase associated motor 16 like Neighboring gene STARR-seq mESC enhancer starr_26515 Neighboring gene STARR-positive B cell enhancer ABC_E10603 Neighboring gene STARR-positive B cell enhancer ABC_E6836 Neighboring gene STARR-positive B cell enhancer ABC_E6837 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:43301229-43301412 Neighboring gene CD24a antigen Neighboring gene RIKEN cDNA F930017D23 gene Neighboring gene predicted gene, 51800

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Reymond A, et al. Genomics, 2001 Nov. PMID 11707072
  2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
  3. Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers. Wang C, et al. FASEB J, 2019 Aug. PMID 31162944, Free PMC Article
  4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding ISO
Inferred from Sequence Orthology
more info
  
enables ribosomal large subunit binding ISO
Inferred from Sequence Orthology
more info
  
enables tRNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of mitochondrial transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of mitochondrial transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in rescue of stalled ribosome ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
mitochondrial transcription rescue factor 1
Names
uncharacterized protein C6orf203 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026411.2 → NP_080687.1  mitochondrial transcription rescue factor 1

    See identical proteins and their annotated locations for NP_080687.1

    Status: VALIDATED

    Source sequence(s)
    AC159462, AK006199, DV045344
    Consensus CDS
    CCDS23820.1
    UniProtKB/Swiss-Prot
    Q3TQU4, Q9CQF4
    Related
    ENSMUSP00000119053.3, ENSMUST00000147196.3
    Conserved Domains (1) summary
    TIGR03069
    Location:133 → 227
    PS_II_S4; photosystem II S4 domain protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    43401115..43417037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512833.5 → XP_006512896.1  mitochondrial transcription rescue factor 1 isoform X1

    See identical proteins and their annotated locations for XP_006512896.1

    UniProtKB/Swiss-Prot
    Q3TQU4, Q9CQF4
    Conserved Domains (1) summary
    TIGR03069
    Location:133 → 227
    PS_II_S4; photosystem II S4 domain protein

  2. XM_006512834.4 → XP_006512897.1  mitochondrial transcription rescue factor 1 isoform X1

    See identical proteins and their annotated locations for XP_006512897.1

    UniProtKB/Swiss-Prot
    Q3TQU4, Q9CQF4
    Conserved Domains (1) summary
    TIGR03069
    Location:133 → 227
    PS_II_S4; photosystem II S4 domain protein

  3. XM_017314069.2 → XP_017169558.1  mitochondrial transcription rescue factor 1 isoform X1

    UniProtKB/Swiss-Prot
    Q3TQU4, Q9CQF4
    Conserved Domains (1) summary
    TIGR03069
    Location:133 → 227
    PS_II_S4; photosystem II S4 domain protein

  4. XM_011243202.2 → XP_011241504.1  mitochondrial transcription rescue factor 1 isoform X2

    Conserved Domains (1) summary
    COG2302
    Location:131 → 186
    YlmH; RNA-binding protein YlmH, contains S4-like domain [General function prediction only]

RNA

  1. XR_004936264.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQF4.1 GenPept UniProtKB/Swiss-Prot:Q9CQF4

Gene LinkOut

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