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Ribc2 RIB43A domain with coiled-coils 2 [ Mus musculus (house mouse) ]

Gene ID: 67747, updated on 5-Mar-2024

Summary

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Official Symbol
Ribc2provided by MGI
Official Full Name
RIB43A domain with coiled-coils 2provided by MGI
Primary source
MGI:MGI:1914997
See related
Ensembl:ENSMUSG00000022431 AllianceGenome:MGI:1914997
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Trib; 4930579A10Rik
Summary
Is expressed in bladder wall; diaphragm; ilio-psoas; skeleton; and tail mesenchyme. Orthologous to human RIBC2 (RIB43A domain with coiled-coils 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 6.1) and bladder adult (RPKM 0.1) See more
Orthologs
human all
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Genomic context

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Location:
15 E2; 15 40.25 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (85016261..85028771)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (85132060..85144570)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52194 Neighboring gene uroplakin 3A Neighboring gene family with sequence similarity 118, member A Neighboring gene STARR-seq mESC enhancer starr_39377 Neighboring gene structural maintenance of chromosomes 1B Neighboring gene ribosomal protein L23A pseudogene Neighboring gene predicted gene, 19277 Neighboring gene fibulin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene. Arango NA, et al. Gene, 2004 Dec 8. PMID 15563848
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genomic structure and expression profile of mouse Trib and comparison of its homology with other ribbon proteins.
    Title: Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene.
  2. Trib expression is testis-specific and appears to be found only in the germ cells during the leptotene-pachytene stages of spermatogenesis.
    Title: Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC130587

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in axonemal A tubule inner sheath IDA
Inferred from Direct Assay
more info
 PubMed 
located_in axonemal microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RIB43A-like with coiled-coils protein 2
Names
testis-specific ribbon protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026357.2 → NP_080633.2  RIB43A-like with coiled-coils protein 2

    See identical proteins and their annotated locations for NP_080633.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein coding variant.
    Source sequence(s)
    AK016311, BY716712
    Consensus CDS
    CCDS49689.1
    UniProtKB/Swiss-Prot
    G3X8W0, Q9D4Q1
    Related
    ENSMUSP00000023067.3, ENSMUST00000023067.4
    Conserved Domains (1) summary
    pfam05914
    Location:3 → 377
    RIB43A

RNA

  1. NR_152195.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL772308
    Related
    ENSMUST00000229238.2

  2. NR_164346.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL772308

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    85016261..85028771
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159551.1 → XP_036015444.1  RIB43A-like with coiled-coils protein 2 isoform X1

    Conserved Domains (1) summary
    pfam05914
    Location:6 → 204
    RIB43A

  2. XM_036159552.1 → XP_036015445.1  RIB43A-like with coiled-coils protein 2 isoform X1

    Conserved Domains (1) summary
    pfam05914
    Location:6 → 204
    RIB43A

  3. XM_036159553.1 → XP_036015446.1  RIB43A-like with coiled-coils protein 2 isoform X1

    Conserved Domains (1) summary
    pfam05914
    Location:6 → 204
    RIB43A

RNA

  1. XR_004938865.1 RNA Sequence

  2. XR_004938866.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D4Q1.3 GenPept UniProtKB/Swiss-Prot:Q9D4Q1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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