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Pcnx4 pecanex homolog 4 [ Mus musculus (house mouse) ]

Gene ID: 67708, updated on 3-Apr-2024

Summary

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Official Symbol
Pcnx4provided by MGI
Official Full Name
pecanex homolog 4provided by MGI
Primary source
MGI:MGI:1914958
See related
Ensembl:ENSMUSG00000034501 AllianceGenome:MGI:1914958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pcnxl4; 4932413O10; 1810048J11Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human PCNX4 (pecanex 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 6.0), whole brain E14.5 (RPKM 4.7) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
12 C3; 12 30.2 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (72583098..72628555)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (72536152..72580213)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33487 Neighboring gene leucine rich repeat containing 9 Neighboring gene STARR-seq mESC enhancer starr_32441 Neighboring gene lymphocyte antigen 6 family member E, pseudogene 1 Neighboring gene dehydrogenase/reductase 7 like 1 Neighboring gene STARR-seq mESC enhancer starr_32442 Neighboring gene dehydrogenase/reductase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
pecanex-like protein 4
Names
pecanex homolog protein 4
pecanex-like 4
pecanex-like protein C14orf135 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001404745.1 → NP_001391674.1  pecanex-like protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC160936

  2. NM_001404746.1 → NP_001391675.1  pecanex-like protein 4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC160936

  3. NM_001404747.1 → NP_001391676.1  pecanex-like protein 4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC160936

  4. NM_001404748.1 → NP_001391677.1  pecanex-like protein 4 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC160936

  5. NM_001404750.1 → NP_001391679.1  pecanex-like protein 4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160936

  6. NM_001404752.1 → NP_001391681.1  pecanex-like protein 4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160936

  7. NM_001404753.1 → NP_001391682.1  pecanex-like protein 4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160936

  8. NM_001404754.1 → NP_001391683.1  pecanex-like protein 4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160936

  9. NM_026327.4 → NP_080603.2  pecanex-like protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC160936
    Consensus CDS
    CCDS36473.1
    UniProtKB/Swiss-Prot
    Q3TUC5, Q3UVY5, Q8BPG1, Q8VE84, Q9D8P3
    UniProtKB/TrEMBL
    E9QN69
    Related
    ENSMUSP00000038916.7, ENSMUST00000044352.8
    Conserved Domains (1) summary
    pfam05041
    Location:1059 → 1174
    Pecanex_C; Pecanex protein (C-terminus)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    72583098..72628555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516177.4 → XP_006516240.1  pecanex-like protein 4 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UVY5.2 GenPept UniProtKB/Swiss-Prot:Q3UVY5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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