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Luc7l3 LUC7-like 3 (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 67684, updated on 30-Apr-2024

Summary

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Official Symbol
Luc7l3provided by MGI
Official Full Name
LUC7-like 3 (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:1914934
See related
Ensembl:ENSMUSG00000020863 AllianceGenome:MGI:1914934
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Luc7a; 3300001P08Rik
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site selection. Predicted to act upstream of or within mRNA processing. Predicted to be located in nuclear speck. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is expressed in central nervous system and retina. Orthologous to human LUC7L3 (LUC7 like 3 pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E14 (RPKM 59.6), CNS E11.5 (RPKM 55.5) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 58.9 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94181899..94213196, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94291073..94322329, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30463 Neighboring gene STARR-positive B cell enhancer ABC_E11487 Neighboring gene predicted gene, 38956 Neighboring gene ANKRD40 C-terminal like Neighboring gene STARR-positive B cell enhancer ABC_E5270 Neighboring gene STARR-positive B cell enhancer ABC_E7046 Neighboring gene ankyrin repeat domain 40 Neighboring gene ATP-binding cassette, sub-family C member 3 Neighboring gene predicted gene, 51871

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Charles CH, et al. Oncogene, 1992 Jan. PMID 1741163
  2. Comprehensive interactome of Otx2 in the adult mouse neural retina. Fant B, et al. Genesis, 2015 Nov. PMID 26426291
  3. The sperm-associated antigen 6 interactome and its role in spermatogenesis. Liu Y, et al. Reproduction, 2019 Aug. PMID 31146259, Free PMC Article
  4. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article
  5. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Murn J, et al. Genes Dev, 2015 Mar 1. PMID 25737280, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in RNA splicing ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
luc7-like protein 3
Names
cisplatin resistance-associated overexpressed protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361573.1 → NP_001348502.1  luc7-like protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK019464, AK043494, AK151228
    Consensus CDS
    CCDS88224.1
    Related
    ENSMUSP00000129919.2, ENSMUST00000166312.8
    Conserved Domains (1) summary
    pfam03194
    Location:4 → 233
    LUC7; LUC7 N_terminus

  2. NM_001361574.1 → NP_001348503.1  luc7-like protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL645846, AL645965
    Consensus CDS
    CCDS88223.1
    UniProtKB/Swiss-Prot
    Q3U9D5, Q5SUF2, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4
    Related
    ENSMUSP00000103450.2, ENSMUST00000107820.2
    Conserved Domains (1) summary
    pfam03194
    Location:4 → 233
    LUC7; LUC7 N_terminus

  3. NM_001361575.1 → NP_001348504.1  luc7-like protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL645846, AL645965
    Consensus CDS
    CCDS88223.1
    UniProtKB/Swiss-Prot
    Q3U9D5, Q5SUF2, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4
    Related
    ENSMUSP00000103451.3, ENSMUST00000107821.9
    Conserved Domains (1) summary
    pfam03194
    Location:4 → 233
    LUC7; LUC7 N_terminus

  4. NM_026313.2 → NP_080589.1  luc7-like protein 3 isoform 1

    See identical proteins and their annotated locations for NP_080589.1

    Status: VALIDATED

    Source sequence(s)
    AL645846, AL645965
    Consensus CDS
    CCDS25252.1
    UniProtKB/Swiss-Prot
    Q5SUF2
    Related
    ENSMUSP00000021226.8, ENSMUST00000021226.14
    Conserved Domains (1) summary
    pfam03194
    Location:4 → 233
    LUC7; LUC7 N_terminus

RNA

  1. NR_155068.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL645846, AL645965

  2. NR_155069.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL645846, AL645965

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    94181899..94213196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156917.1 → XP_036012810.1  luc7-like protein 3 isoform X3

    Conserved Domains (1) summary
    cl27291
    Location:1 → 58
    LUC7; LUC7 N_terminus

  2. XM_036156915.1 → XP_036012808.1  luc7-like protein 3 isoform X1

    Conserved Domains (1) summary
    pfam03194
    Location:4 → 170
    LUC7; LUC7 N_terminus

  3. XM_036156916.1 → XP_036012809.1  luc7-like protein 3 isoform X2

    Conserved Domains (1) summary
    cl27291
    Location:4 → 170
    LUC7; LUC7 N_terminus

RNA

  1. XR_001780043.3 RNA Sequence

  2. XR_001780044.3 RNA Sequence

  3. XR_388511.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SUF2.1 GenPept UniProtKB/Swiss-Prot:Q5SUF2

Gene LinkOut

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