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Zfp605 zinc finger protein 605 [ Mus musculus (house mouse) ]

Gene ID: 675812, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp605provided by MGI
Official Full Name
zinc finger protein 605provided by MGI
Primary source
MGI:MGI:2444933
See related
Ensembl:ENSMUSG00000023284 AllianceGenome:MGI:2444933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A830023I12Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF605 (zinc finger protein 605). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 2.5), CNS E14 (RPKM 2.3) and 21 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 F; 5 53.3 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (110257898..110279402)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (110110028..110131536)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54335 Neighboring gene STARR-positive B cell enhancer ABC_E4778 Neighboring gene STARR-positive B cell enhancer ABC_E10339 Neighboring gene STARR-positive B cell enhancer ABC_E3597 Neighboring gene phosphatidylinositol-specific phospholipase C, X domain containing 1 Neighboring gene GTP binding protein 6 (putative) Neighboring gene nucleophosmin pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6362 Neighboring gene STARR-seq mESC enhancer starr_13946 Neighboring gene checkpoint with forkhead and ring finger domains Neighboring gene STARR-positive B cell enhancer mm9_chr5:110605377-110605678 Neighboring gene predicted gene 15787 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:110605669-110605852 Neighboring gene golgin A3 Neighboring gene uncharacterized LOC118568795

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genomic variants in an inbred mouse model predict mania-like behaviors. Saul MC, et al. PLoS One, 2018. PMID 29768498, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1)  1 citation
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC7438

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 605

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163996.1 → NP_001157468.1  zinc finger protein 605

    See identical proteins and their annotated locations for NP_001157468.1

    Status: VALIDATED

    Source sequence(s)
    AC166747, AK043719
    Consensus CDS
    CCDS51605.1
    UniProtKB/TrEMBL
    E9QAH2, F6VFU8
    Related
    ENSMUSP00000108147.2, ENSMUST00000112528.8
    Conserved Domains (3) summary
    smart00349
    Location:7 → 62
    KRAB; krueppel associated box
    COG5048
    Location:331 → 693
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:473 → 493
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    110257898..110279402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535186.5 → XP_006535249.1  zinc finger protein 605 isoform X1

    See identical proteins and their annotated locations for XP_006535249.1

    UniProtKB/TrEMBL
    E9QAH2, F6VFU8
    Conserved Domains (3) summary
    smart00349
    Location:7 → 62
    KRAB; krueppel associated box
    COG5048
    Location:331 → 693
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:473 → 493
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_006535188.4 → XP_006535251.1  zinc finger protein 605 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:266 → 628
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:408 → 428
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_036165438.1 → XP_036021331.1  zinc finger protein 605 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:266 → 628
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:408 → 428
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_006535187.5 → XP_006535250.1  zinc finger protein 605 isoform X1

    See identical proteins and their annotated locations for XP_006535250.1

    UniProtKB/TrEMBL
    E9QAH2, F6VFU8
    Conserved Domains (3) summary
    smart00349
    Location:7 → 62
    KRAB; krueppel associated box
    COG5048
    Location:331 → 693
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:473 → 493
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_036165437.1 → XP_036021330.1  zinc finger protein 605 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:266 → 628
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:408 → 428
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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