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Gstcd glutathione S-transferase, C-terminal domain containing [ Mus musculus (house mouse) ]

Gene ID: 67553, updated on 11-Apr-2024

Summary

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Official Symbol
Gstcdprovided by MGI
Official Full Name
glutathione S-transferase, C-terminal domain containingprovided by MGI
Primary source
MGI:MGI:1914803
See related
Ensembl:ENSMUSG00000028018 AllianceGenome:MGI:1914803
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933434L15Rik
Summary
Predicted to be active in cytoplasm. Is expressed in testis. Orthologous to human GSTCD (glutathione S-transferase C-terminal domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.0), testis adult (RPKM 6.2) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 G3; 3 61.54 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (132687511..132797800, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (132981750..133092039, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09020 Neighboring gene predicted gene, 29811 Neighboring gene heat shock protein 90 alpha (cytosolic), class B member 1 pseudogene Neighboring gene nephronectin Neighboring gene predicted gene, 23196 Neighboring gene TIP41, TOR signalling pathway regulator-like pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6130 Neighboring gene STARR-positive B cell enhancer ABC_E9573 Neighboring gene STARR-positive B cell enhancer mm9_chr3:132754721-132755022 Neighboring gene STARR-positive B cell enhancer ABC_E11218 Neighboring gene integrator complex subunit 12 Neighboring gene Rho guanine nucleotide exchange factor 38 Neighboring gene STARR-seq mESC enhancer starr_09022 Neighboring gene predicted gene, 52616 Neighboring gene STARR-positive B cell enhancer ABC_E10215 Neighboring gene STARR-positive B cell enhancer ABC_E4594 Neighboring gene STARR-positive B cell enhancer ABC_E4595 Neighboring gene STARR-positive B cell enhancer ABC_E9574 Neighboring gene STARR-seq mESC enhancer starr_09023 Neighboring gene pyrophosphatase (inorganic) 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice. Liu B, et al. PLoS One, 2019. PMID 31513609, Free PMC Article
  2. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
  3. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC74393

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
glutathione S-transferase C-terminal domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356309.1 → NP_001343238.1  glutathione S-transferase C-terminal domain-containing protein

    Status: VALIDATED

    Source sequence(s)
    AC124593, BC061240
    Consensus CDS
    CCDS17847.1
    UniProtKB/Swiss-Prot
    Q5RL51, Q6P8I1, Q8BXR2, Q8BYY6, Q9CTV2, Q9CUA9, Q9CXU7
    Related
    ENSMUSP00000079421.6, ENSMUST00000080583.6
    Conserved Domains (2) summary
    cl02776
    Location:271 → 330
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
    cl17173
    Location:424 → 542
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. NM_026231.3 → NP_080507.2  glutathione S-transferase C-terminal domain-containing protein

    See identical proteins and their annotated locations for NP_080507.2

    Status: VALIDATED

    Source sequence(s)
    AC124593, BC047136, BY740821
    Consensus CDS
    CCDS17847.1
    UniProtKB/Swiss-Prot
    Q5RL51, Q6P8I1, Q8BXR2, Q8BYY6, Q9CTV2, Q9CUA9, Q9CXU7
    Related
    ENSMUSP00000029651.5, ENSMUST00000029651.11
    Conserved Domains (2) summary
    cl02776
    Location:271 → 330
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
    cl17173
    Location:424 → 542
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    132687511..132797800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003954372.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RL51.1 GenPept UniProtKB/Swiss-Prot:Q5RL51

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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