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P3r3urf Pik3r3 upstream reading frame [ Mus musculus (house mouse) ]

Gene ID: 67323, updated on 16-Mar-2024

Summary

Official Symbol
P3r3urfprovided by MGI
Official Full Name
Pik3r3 upstream reading frameprovided by MGI
Primary source
MGI:MGI:1914573
See related
Ensembl:ENSMUSG00000078593 AllianceGenome:MGI:1914573
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700042G07Rik
Summary
Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity and phosphotyrosine residue binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Orthologous to several human genes including PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 179.1) See more
Orthologs
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Genomic context

Location:
4 D1; 4 53.1 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116030569..116031494)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116173372..116174297)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Neighboring gene tetraspanin 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:115849369-115849478 Neighboring gene STARR-seq mESC enhancer starr_11134 Neighboring gene LLP homolog, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_11135 Neighboring gene STARR-positive B cell enhancer ABC_E838 Neighboring gene phosphoinositide-3-kinase regulatory subunit 3 Neighboring gene BRCA1 associated RING domain 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
PIK3R3 upstream open reading frame protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099295.2NP_001092765.1  PIK3R3 upstream open reading frame protein

    See identical proteins and their annotated locations for NP_001092765.1

    Status: VALIDATED

    Source sequence(s)
    AK006685, BU946248
    Consensus CDS
    CCDS51276.1
    UniProtKB/Swiss-Prot
    B1AUF7
    Related
    ENSMUSP00000102101.3, ENSMUST00000106492.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116030569..116031494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)