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Zc2hc1a zinc finger, C2HC-type containing 1A [ Mus musculus (house mouse) ]

Gene ID: 67306, updated on 3-Apr-2024

Summary

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Official Symbol
Zc2hc1aprovided by MGI
Official Full Name
zinc finger, C2HC-type containing 1Aprovided by MGI
Primary source
MGI:MGI:1914556
See related
Ensembl:ENSMUSG00000043542 AllianceGenome:MGI:1914556
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam164a; 3110050N22Rik
Summary
Predicted to enable metal ion binding activity. Is expressed in central nervous system; dorsal root ganglion; early conceptus; olfactory epithelium; and oocyte. Orthologous to human ZC2HC1A (zinc finger C2HC-type containing 1A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 22.4), whole brain E14.5 (RPKM 18.1) and 16 other tissues See more
Orthologs
human all
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Genomic context

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See Zc2hc1a in Genome Data Viewer
Location:
3 A1; 3 2.01 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (7568475..7618908)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (7503415..7553848)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-like domain containing CTD phosphatase 1 pseudogene Neighboring gene predicted gene, 23592 Neighboring gene STARR-seq mESC enhancer starr_06837 Neighboring gene STARR-seq mESC enhancer starr_06838 Neighboring gene STARR-seq mESC enhancer starr_06840 Neighboring gene interleukin 7 Neighboring gene predicted gene, 16685 Neighboring gene STARR-seq mESC enhancer starr_06841 Neighboring gene STARR-seq mESC enhancer starr_06842 Neighboring gene STARR-seq mESC enhancer starr_06843 Neighboring gene STARR-seq mESC enhancer starr_06844 Neighboring gene STARR-seq mESC enhancer starr_06846 Neighboring gene STARR-seq mESC enhancer starr_06847 Neighboring gene predicted gene, 29747

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Bulfone A, et al. J Neurosci, 2005 Aug 17. PMID 16107646, Free PMC Article
  2. ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease. Cozzolino F, et al. Hum Mol Genet, 2021 Jun 17. PMID 33601422
  3. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca(2+)/CaM) and CaM Kinase II (CaMKII) Binding Partner. Evans PR, et al. J Proteome Res, 2018 Apr 6. PMID 29518331, Free PMC Article
  4. Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. Srivastava A, et al. J Biosci, 2020. PMID 32098917
  5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC90536

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
zinc finger C2HC domain-containing protein 1A
Names
family with sequence similarity 164, member A
protein FAM164A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001428956.1 → NP_001415885.1  zinc finger C2HC domain-containing protein 1A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC123876, AC125373

  2. NM_173181.4 → NP_775273.1  zinc finger C2HC domain-containing protein 1A isoform 1

    See identical proteins and their annotated locations for NP_775273.1

    Status: VALIDATED

    Source sequence(s)
    AC123876, AC125373
    Consensus CDS
    CCDS17230.1
    UniProtKB/Swiss-Prot
    Q3TCP6, Q8BJH1
    Related
    ENSMUSP00000054734.4, ENSMUST00000051064.9
    Conserved Domains (2) summary
    pfam09786
    Location:149 → 293
    CytochromB561_N; Cytochrome B561, N terminal
    pfam13913
    Location:15 → 39
    zf-C2HC_2; zinc-finger of a C2HC-type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    7568475..7618908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530086.1 → XP_006530149.1  zinc finger C2HC domain-containing protein 1A isoform X1

    Conserved Domains (2) summary
    PRK12495
    Location:122 → 234
    PRK12495; hypothetical protein; Provisional
    pfam13913
    Location:15 → 39
    zf-C2HC_2; zinc-finger of a C2HC-type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BJH1.1 GenPept UniProtKB/Swiss-Prot:Q8BJH1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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